Nonketotic hyperglycemic coma
Hyperosmolar diabetic coma (HNDC) is a rare, severe acute complication of diabetes, which is more common in elderly patients with no history of diabetes or mild non-insulin-dependent diabetes, but can also be seen in patients with insulin-dependent diabetes. The patient's original insulin secretion is insufficient, and the blood sugar rises rapidly under the influence of inducements, which promotes the aggravation of sugar metabolism disorders, causing the extracellular fluid to be hyperosmotic, hypovolemic hyperosmotic dehydration, and the original arteriosclerosis causing insufficient blood supply and hypoxia in the cerebral cortex, resulting in mental and neurological symptoms and coma.
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Site of disease:
Brain Pancreas
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Infectious :
Not contagious
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Frequent population:
Elderly people, those with decreased renal function
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Related symptoms:
Polydipsia
polyuria
drowsiness
thirst and polydipsia
breath may smell like rotten apples
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Concurrent disease:
Related Drugs
Glimepiride Tablets
Indication: It is suitable for type 2 diabetes mellitus in which diet control, exercise therapy and weight loss cannot satisfactorily control blood sugar.
Sodium Chloride Injection
Indication: It is suitable for water loss caused by various reasons, including hypotonic, isotonic and hypertonic water loss; hyperosmotic non-ketotic diabetic coma, the application of isotonic or hypotonic sodium chloride can correct water loss and hyperosmotic state; hypochloremic metabolic alkalosis; external use of normal saline to rinse eyes, wash wounds, etc.; it is also used for obstetric water bag induction of labor.
Manufacturer:
Shijiazhuang No.4 Pharmaceutical Co., Ltd.
Sodium Chloride Injection
Indication: It is suitable for water loss caused by various reasons, including hypotonic, isotonic and hypertonic water loss; hypertonic non-ketotic diabetic coma can be corrected by using isotonic or hypotonic sodium chloride; hypochloremic metabolic alkalosis; external use of normal saline to wash eyes and wounds, etc.; it is also used for water bag induction in obstetrics
Manufacturer:
Shijiazhuang No.4 Pharmaceutical Co., Ltd.
Sodium Chloride Injection
Indication: It is suitable for water loss caused by various reasons, including hypotonic, isotonic and hypertonic water loss; hypertonic non-ketotic diabetic coma can be corrected by using isotonic or hypotonic sodium chloride; hypochloremic metabolic alkalosis; external use of normal saline to wash eyes and wounds, etc.; it is also used for water bag induction in obstetrics
Manufacturer:
Shandong Kelun Phaemaceutical Co., Ltd.
Glipizide Tablets
Indication: Used for type 2 diabetes.
Manufacturer:
GRAND PHARMACEUTICAL(China) Co., Ltd.
Metformin Hydrochloride Tablets
Indication: 1. This product is first used for type 2 diabetes that is ineffective with simple diet control and physical exercise, especially obese type 2 diabetes. 2. For type 1 or type 2 diabetes, this product combined with insulin can increase the hypoglycemic effect of insulin, reduce insulin dosage, and prevent hypoglycemia. 3. This product can also be used in combination with sulfonylurea oral hypoglycemic drugs to have a synergistic effect.
Manufacturer:
SINO-AMERICAN Shanghai Squibb Pharmaceuticals Ltd.
Metformin Hydrochloride Tablets
Indication: 1. This product is first used for type 2 diabetes that is ineffective with simple diet control and physical exercise, especially obese type 2 diabetes. 2. For type 1 or type 2 diabetes, this product combined with insulin can increase the hypoglycemic effect of insulin, reduce insulin dosage, and prevent hypoglycemia. 3. This product can also be used in combination with sulfonylurea oral hypoglycemic drugs to have a synergistic effect.
Manufacturer:
SINO-AMERICAN Shanghai Squibb Pharmaceuticals Ltd.
Compound Sodium Chloride Injection
Indication: 1 Water loss due to various reasons, including hypotonic, isotonic and hypertonic water loss; 2 Hyperosmotic non-ketotic coma, the use of isotonic or hypotonic sodium chloride can correct water loss and hyperosmotic state; 3 Hypochloremic metabolic alkalosis. When the patient cannot eat or eats less for some reason and needs to supplement the daily physiological needs, sodium chloride injection or compound sodium chloride injection can generally be given. Because this product contains very little potassium, hypokalemia needs to be supplemented as needed.
Manufacturer:
Shijiazhuang No.4 Pharmaceutical Co., Ltd.
Phenformin Hydrochloride Tablets
Indication: It is used for type 2 diabetes patients who are not satisfied with diet control alone, especially obese patients and patients with hyperinsulinemia. This product not only has the effect of lowering blood sugar, but also may help to reduce weight and hyperinsulinemia. For some diabetic patients who have poor response to sulfonylurea treatment, this product combined with sulfonylurea hypoglycemic drugs can produce a synergistic effect, which is better than the effect of using each alone.