Megaloblastic anemia
Megaloblastic anemia is a group of anemias caused by disorders in the synthesis of deoxyribonucleic acid (DNA). It is mainly caused by a lack of vitamin B12 or folic acid in the body. It can also be caused by inherited or drug-induced DNA synthesis disorders. About 95% of cases are nutritional anemias caused by a lack of folic acid or (and) vitamin B12. In the early stages, it is not uncommon to see patients with simple folic acid or vitamin B12 deficiency. Nutritional megaloblastic anemia is regional. It is more common in the northwest of my country, such as Shanxi and Shaanxi Provinces, with a prevalence of up to 5.3%. Pernicious anemia is rare in my country.
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Site of disease:
Blood vessels throughout the body -
Infectious :
Not contagious -
Frequent population:
Teenagers, pregnant women -
Related symptoms:
Shortness of breath eyelid swelling bleeding tendency weakness depression -
Concurrent disease:
Related Drugs
Calcium folinate for injection
Indication: It is mainly used as an antidote for folic acid antagonists (such as methotrexate, pyrimethamine or trimethoprim). This product is often used clinically to prevent severe toxic effects caused by overdose or high-dose treatment of methotrexate. When oral folic acid is ineffective, it is also used for megaloblastic anemia caused by stomatitis, diarrhea, malnutrition, pregnancy or infancy, but it is not suitable for vitamin B12 deficiency anemia. In recent years, calcium folinate has been used as an adjuvant treatment for colon and rectal cancer, and combined with fluorouracil, it can prolong survival.
Manufacturer:
Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment for neuritis.
Manufacturer:
Jiangsu Sihuan Bioengineering Pharmaceutical Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia caused by intrinsic factor deficiency, and can also be used as an adjuvant treatment for subacute combined degenerative nervous system diseases such as neuritis.
Manufacturer:
Shandong FANGMING Pharmaceutical Group Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment for neuritis.
Manufacturer:
Yusongyuan Pharmaceutical Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment for neuritis.
Manufacturer:
Shanghai JINDI Jiuzhou (Anyang) Pharmaceutical Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment for neuritis.
Manufacturer:
Hubei Jinyao Pharmaceutical Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment for neuritis.
Manufacturer:
Southwest Pharmaceutical Co., Ltd.
Vitamin B12 Injection
Indication: It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment for neuritis.
Manufacturer:
Shanxi JINXIN DOUBLE-CRANE Pharmaceutical Co., Ltd.
Calcium Folinate and Sodium Chloride Injection
Indication: 1. Used as an antidote for folic acid antagonists (such as methotrexate, pyrimethamine or trimethoprim, etc.). 2. Used to prevent and treat severe toxic effects caused by excessive or high-dose treatment with methotrexate. 3. Megaloblastic anemia caused by folic acid deficiency. 4. Used in combination with 5-fluorouracil to treat advanced colorectal cancer.
Calcium Folinate and Sodium Chloride Injection
Indication: 1. Used as an antidote for folic acid antagonists (such as methotrexate, pyrimethamine or trimethoprim, etc.). 2. Used to prevent and treat severe toxic effects caused by excessive or high-dose treatment with methotrexate. 3. Megaloblastic anemia caused by folic acid deficiency. 4. Used in combination with 5-fluorouracil to treat advanced colorectal cancer.
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