No specific pharmacological effects mentioned

It has an antibacterial effect only on Mycobacterium tuberculosis. It inhibits the growth and reproduction of Mycobacterium tuberculosis by competitively inhibiting the synthesis of folic acid.

By inhibiting bacterial transpeptidase, it prevents the synthesis of bacterial cell walls and inhibits or kills bacteria. When used in combination with trimethoprim, it can enhance antibacterial ability, delay the development of drug resistance, and reduce oral dosage.

By inhibiting bacterial transpeptidase, it prevents the synthesis of bacterial cell walls and inhibits or kills bacteria. When used in combination with cephalexin, it can enhance antibacterial ability, delay the development of drug resistance, and reduce oral dosage.

Extract from the above information

It has a significant bactericidal effect on Mycobacterium tuberculosis and some non-tuberculous mycobacteria (including Mycobacterium leprae, etc.) both inside and outside the host cells. It firmly binds to the β subunit of the DNA-dependent RNA polymerase, inhibits the synthesis of bacterial RNA, prevents the enzyme from connecting to DNA, thereby blocking the RNA transcription process and stopping the synthesis of DNA and protein.

It has a highly selective bactericidal effect on all types of Mycobacterium tuberculosis, with a strong effect on Mycobacterium tuberculosis in the growth and reproduction stage, and a weaker and slower effect on Mycobacterium tuberculosis in the dormant stage. The mechanism of action may be to inhibit the synthesis of mycolic acid in sensitive bacteria and cause the cell wall to rupture.