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Founded in:
2002-01-28 -
Country:
China -
Address:
No. 55, Songshan Street, Taihe District, Jinzhou City, Liaoning Province -
Tax NO.:
91210700734224812X -
Registered Funds:
660 million yuan -
Website:
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Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Pralidoxime Chloride |
This product is an oxime compound. Its quaternary ammonium group can tend to the cationic site of the phosphorylated cholinesterase that has lost its activity and is combined with the organophosphorus insecticide. Its nucleophilic group can directly combine with the phosphorylated group of cholinesterase and then detach from the cholinesterase together, so that the cholinesterase returns to its original state and regains its activity. It has a significant effect on the nicotine-like symptoms caused by organophosphorus insecticides, but a weak effect on the phytosaminoglycan-like symptoms, and has no significant effect on the symptoms of the central nervous system.
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This product is an oxime compound. Its quaternary ammonium group can tend to the cationic site of the phosphorylated cholinesterase that has lost its activity and is combined with the organophosphorus insecticide. Its nucleophilic group can directly combine with the phosphorylated group of cholinesterase and then detach from the cholinesterase together, so that the cholinesterase returns to its original state and regains its activity. It has a significant effect on the nicotine-like symptoms caused by organophosphorus insecticides, but a weak effect on the phytosaminoglycan-like symptoms, and has no significant effect on the symptoms of the central nervous system. |
79.5% | 51-15-0 | 12 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Organophosphates |
It combines with cholinesterase in the body to form phosphoacylase, causing it to lose the ability to hydrolyze acetylcholine, leading to accumulation of acetylcholine and the appearance of poisoning symptoms. Antidotes such as pralidoxime iodide can combine with the phosphoryl group in phosphocholinesterase to restore cholinesterase activity and eliminate muscle tremors and spasms, but have poor effects on salivation and sweating. At the same time, it can directly combine with organophosphates in the blood to form non-toxic substances that are excreted in the urine.
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It combines with cholinesterase in the body to form phosphoacylase, causing it to lose the ability to hydrolyze acetylcholine, leading to accumulation of acetylcholine and the appearance of poisoning symptoms. Antidotes such as pralidoxime iodide can combine with the phosphoryl group in phosphocholinesterase to restore cholinesterase activity and eliminate muscle tremors and spasms, but have poor effects on salivation and sweating. At the same time, it can directly combine with organophosphates in the blood to form non-toxic substances that are excreted in the urine. |
0 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Organophosphates |
It combines with cholinesterase in the body to form a phosphoacylase, causing it to lose the ability to hydrolyze acetylcholine, leading to accumulation of acetylcholine and the appearance of poisoning symptoms. Antidotes such as pralidoxime iodide can combine with the phosphoryl group in the phosphocholinesterase to restore the activity of cholinesterase and have a significant effect in eliminating muscle tremors and spasms, but have a poor effect on salivation and sweating, and need to be used as early as possible.
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It combines with cholinesterase in the body to form a phosphoacylase, causing it to lose the ability to hydrolyze acetylcholine, leading to accumulation of acetylcholine and the appearance of poisoning symptoms. Antidotes such as pralidoxime iodide can combine with the phosphoryl group in the phosphocholinesterase to restore the activity of cholinesterase and have a significant effect in eliminating muscle tremors and spasms, but have a poor effect on salivation and sweating, and need to be used as early as possible. |
0 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Dipyridamole |
It has anti-thrombotic effect. Dipyridamole inhibits platelet aggregation, and high concentration (50μg/ml) can inhibit platelet release. The mechanism of action may be (1) inhibiting platelet uptake of adenosine, which is a platelet reaction inhibitor; (2) inhibiting phosphodiesterase, increasing cyclic adenosine monophosphate (cAMP) in platelets; (3) inhibiting the formation of thromboxane A2 (TXA2), a strong agonist of TXA2 platelet activity; (4) enhancing endogenous PGI2. Dipyridamole has a vasodilating effect.
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It has anti-thrombotic effect. Dipyridamole inhibits platelet aggregation, and high concentration (50μg/ml) can inhibit platelet release. The mechanism of action may be (1) inhibiting platelet uptake of adenosine, which is a platelet reaction inhibitor; (2) inhibiting phosphodiesterase, increasing cyclic adenosine monophosphate (cAMP) in platelets; (3) inhibiting the formation of thromboxane A2 (TXA2), a strong agonist of TXA2 platelet activity; (4) enhancing endogenous PGI2. Dipyridamole has a vasodilating effect. |
58-32-2 | 35 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Carbazochrome sodium sulfonate |
No specific description provided
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No specific description provided |
51460-26-5 | 33 |