This product is a non-steroidal anti-inflammatory analgesic, a thiazide derivative, with strong analgesic and anti-inflammatory effects. Its mechanism of action includes: 1. Inhibiting the synthesis of prostaglandins by inhibiting the activity of cyclooxygenase (COX); however, it does not inhibit the activity of 5-lipid oxidase, thus does not inhibit the synthesis of leukotrienes, nor does it divert arachidonic acid to the 5-lipid oxidase pathway. 2. Activating the opioid neuropeptide system to exert a central analgesic effect.

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This product is a potent and highly selective competitive antagonist of 5-hydroxytryptamine 3 (5-HT3) receptors in peripheral neurons and the central nervous system. Certain substances, including some chemotherapy drugs, can stimulate chromaffin cells in the visceral mucosa to release 5-hydroxytryptamine, thereby inducing vomiting reflexes accompanied by nausea. This product mainly inhibits vomiting reflexes by selectively blocking presynaptic 5-HT3 receptors of peripheral neurons. In addition, its antiemetic effect may also be related to its direct blockade of central 5-HT3 receptors to inhibit the stimulation of the vagus nerve in the rear region.

This product is a semi-synthetic 14-membered macrolide antibiotic, and its antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. It is slightly less effective than erythromycin against Gram-positive bacteria, and stronger than erythromycin against Legionella pneumophila. Its antimicrobial effect against Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor (P position), blocking the transfer RNA (t-RNA) from binding to the P position, and also blocking the transfer of the polypeptide chain from the acceptor position (A position) to the P position, thereby inhibiting bacterial protein synthesis.

Azithromycin is a 15-membered macrolide antibiotic that has antibacterial effects on a variety of Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. It mainly binds to the 50S subunit of the bacterial ribosome and inhibits RNA-dependent protein synthesis.