It is an anti-tumor drug belonging to the vinca alkaloid class that inhibits cell division. It acts directly on the dynamic balance of tubulin/microtubules, inhibits the polymerization of tubulin, and causes the disintegration of microtubules during the division phase. It affects axonal microtubules only at high concentrations. Its effect on tubulin spiralization is lower than that of vincristine. It blocks the mitosis of cells in the G2 and M phases, leading to the death of cells entering the interphase or late division phase.

This product is a gastric mucosal protective agent. Under gastric acid conditions, it forms a diffuse protective layer covering the ulcer surface, preventing gastric acid, enzymes and food from invading the ulcer, and promoting the regeneration of the ulcer mucosa and the healing of the ulcer. This product also has the effects of reducing the activity of pepsin, increasing mucin secretion, and promoting the release of PGE2 from the mucosa, thereby protecting the gastric mucosa. In addition, this product has a killing effect on Helicobacter pylori (Hp), thus promoting the healing of gastritis.

Nucleoside antiviral drugs. After entering the cell, this product is rapidly phosphorylated to a monophosphate compound, and then becomes a triphosphate compound through the action of cellular kinase. Its phosphorylation in cells infected with cytomegalovirus is faster than that in normal cells. Ganciclovir can competitively inhibit DNA polymerase and incorporate into the DNA of viruses and host cells, thereby inhibiting DNA synthesis. This product has a stronger inhibitory effect on viral DNA polymerase than host cell polymerase. In animal experiments, this product has teratogenic, carcinogenic, immunosuppressive effects and reproductive system toxicity.

Nucleoside antiviral drugs. After entering the cell, this product is rapidly phosphorylated to a monophosphate compound, and then becomes a triphosphate compound through the action of cellular kinase. Its phosphorylation in cells infected with cytomegalovirus is faster than that in normal cells. Ganciclovir can competitively inhibit DNA polymerase and incorporate into the DNA of viruses and host cells, thereby inhibiting DNA synthesis. This product has a stronger inhibitory effect on viral DNA polymerase than host cell polymerase. In animal experiments, this product has teratogenic, carcinogenic, immunosuppressive effects and reproductive system toxicity.

It is hydrolyzed by phosphamidase or phosphatase in the liver or tumor in the body and becomes activated phosphoramide nitrogen mustard. Its mechanism is to cross-link with DNA, inhibit DNA synthesis, and interfere with RNA function. It is a non-specific drug for the cell cycle. It has a broad anti-tumor spectrum and has inhibitory effects on many tumors.