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By acting on the smooth muscle of the coronary and peripheral blood vessels and the atrioventricular node, inhibiting the influx of Ca2 into the cells, it exhibits vasodilation and prolongs the conduction time of the atrioventricular node, thus being effective for hypertension, arrhythmia, and angina pectoris. 1. Effect on blood pressure: 1) It can reduce hypertension under anesthesia and without anesthesia, but the effect is stronger under anesthesia than without anesthesia, and it has a stronger antihypertensive effect on blood pressure higher than normal blood pressure (rat). 2) While reducing blood pressure, it reduces peripheral vascular resistance and myocardial oxygen consumption, and increases cardiac output (dog). 3) It lowers blood pressure without reducing blood flow to the brain, coronary arteries, and kidneys. It also exhibits a sodium diuretic effect (dog, monkey). 2. Effect on arrhythmia: 1) It prolongs the conduction time, effective refractory period, and functional refractory period of the atrioventricular node, and exhibits an effect on supraventricular tachyarrhythmia (dog). 2) It inhibits supraventricular tachyarrhythmia caused by atrial electrical stimulation (rabbit). 3. Effects on myocardial ischemia: 1) Improve the balance of myocardial oxygen supply and demand ① Dilate the main coronary artery and side branches, increase blood flow to the ischemic part of the myocardium (dogs). ② Inhibit coronary artery spasm (pigs, humans). 2) Myocardial protection When myocardial ischemia occurs, it inhibits excessive influx of Ca2 into cells, maintains cardiac function and myocardial energy metabolism, and reduces the infarct focus (dogs, cats).

It achieves antibacterial effect by inhibiting the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hindering the replication of bacterial DNA. It has good antibacterial effect on most Enterobacteriaceae, some Gram-positive bacteria, Legionella, Mycoplasma, and Chlamydia, but has poor effect on anaerobic bacteria and enterococci.

It prompts the body to increase the plasma concentration of ACTH and cortisone, promotes the blood vessel wall to increase the secretion of PGF2alpha, scavenges free radicals in the body, has anti-inflammatory and anti-exudation effects, increases venous tension, accelerates venous blood flow, promotes lymphatic return, improves blood circulation and microcirculation, and protects the blood vessel wall.

It prompts the body to increase the plasma concentration of ACTH and cortisone, promotes the blood vessel wall to increase the secretion of PGF2alpha, scavenges free radicals in the body, has anti-inflammatory and anti-exudation effects, increases venous tension, accelerates venous blood flow, promotes lymphatic return, improves blood circulation and microcirculation, and protects the blood vessel wall.

It prompts the body to increase the plasma concentration of ACTH and cortisone, promotes the blood vessel wall to increase the secretion of PGF2alpha, scavenges free radicals in the body, has anti-inflammatory and anti-exudation effects, increases venous tension, accelerates venous blood flow, promotes lymphatic return, improves blood circulation and microcirculation, and protects the blood vessel wall.

It prompts the body to increase the plasma concentration of ACTH and cortisone, promotes the blood vessel wall to increase the secretion of PGF2alpha, scavenges free radicals in the body, has anti-inflammatory and anti-exudation effects, increases venous tension, accelerates venous blood flow, promotes lymphatic return, improves blood circulation and microcirculation, and protects the blood vessel wall.