Quinolone antibacterial drugs. It has high antibacterial activity against Enterobacteriaceae such as Escherichia coli, Shigella, Klebsiella, Proteus, Enterobacter, etc.; Haemophilus influenzae and Neisseria gonorrhoeae are also highly sensitive to this product; it also has certain antibacterial effects on Pseudomonas, such as Acinetobacter and Pseudomonas aeruginosa, Staphylococcus, Pneumococcus, and hemolytic Streptococcus. It has a bactericidal effect by acting on the A subunit of DNA helicase in bacterial cells, inhibiting the synthesis and replication of DNA.

This product is a broad-spectrum antibacterial agent with bactericidal effect at high concentrations. In addition to common Gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria, most Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria and spirochetes are also sensitive to this product. This product is better than Gram-positive bacteria for Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, etc. are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant gonococci are also resistant to tetracycline. This product has good antibacterial effect on Gram-negative bacteria such as Vibrio, Yersinia pestis, Brucella, Campylobacter, Yersinia, etc., has no antibacterial activity against Pseudomonas aeruginosa, and has certain antibacterial effect on some anaerobic bacteria, but it is far less significant than other drugs.

This product is a nitrofuran antibacterial drug. It has certain antibacterial effects on both Gram-positive and Gram-negative bacteria, including Salmonella, Shigella, Escherichia coli, Klebsiella pneumoniae, Enterobacter, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, Vibrio cholerae, Campylobacter, Bacteroides, etc. It is also active against Trichomonas and Giardia at a certain concentration. Its mechanism of action is to interfere with bacterial oxidoreductase and thus block the normal metabolism of bacteria.

This product belongs to the macrolide antibiotics, which is the dodecyl sulfate of erythromycin propionate. It has antibacterial activity against Staphylococcus, various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. may also be sensitive to this product. This product also has antibacterial activity against various anaerobic bacteria except Bacteroides fragilis and Fusobacterium; it also has inhibitory effects on Legionella, Campylobacter fetus, some spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product is an antibacterial agent, but it also has a bactericidal effect on some bacteria at high concentrations. This product can pass through the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site (P site), blocking the transfer RNA (t-RNA) binding to the P site, and also blocking the displacement of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis. This product is only effective against bacteria with active division.

It is a vasodilator that can dilate coronary arteries and cerebral blood vessels, reduce myocardial oxygen consumption, improve microcirculation and resist platelet aggregation; it can relax smooth muscles; it has a certain antihypertensive effect on normal and hypertensive animals; it has a significant coronary artery dilation effect, and can dilate normal and spasmodic coronary arteries. After intravenous injection of 30 mg/Kg, coronary blood flow can increase by 40% and vascular resistance can decrease by 29%; it can inhibit thrombin-induced 5-HT release in platelets.