Ursodeoxycholic acid tablets
Function and Efficacy
This product can increase the secretion of bile acid and cause changes in the composition of bile acid, increasing the content of this product in bile. This product can also significantly reduce the molar concentration of cholesterol and cholesterol esters in human bile and the saturation index of cholesterol, thus facilitating the gradual dissolution of cholesterol in stones.
Ingredients
The main ingredient of this product is ursodeoxycholic acid. Its chemical name is 3a,7b-dihydroxy-5b-cholestane-24-acid.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Ursodeoxycholic acidIngredients |
This product can increase the secretion of bile acid and cause changes in the composition of bile acid, increasing the content of this product in bile. This product can also significantly reduce the molar concentration of cholesterol and cholesterol esters in human bile and the saturation index of cholesterol, thus facilitating the gradual dissolution of cholesterol in stones. More |
128-13-2 | 39 |
Appearance
Ursodeoxycholic acid is a white crystalline powder, odorless and bitter. It is almost insoluble in water, easily soluble in ethanol and glacial acetic acid, slightly soluble in imitation, and very slightly soluble in ether. This product is a white tablet.
Indication
This product is used for cholesterol gallstone formation and bile-deficient steatorrhea. It can also be used to prevent drug-induced stone formation and treat steatorrhea (after ileal resection).
Usage and Dosage
Oral administration, choleretic: 50 mg (1 tablet) at a time, 150 mg (3 tablets) per day; cholelithiasis: 450-600 mg (9-12 tablets) per day, taken in 2 divided doses; or 8-10 mg/kg per day according to body weight, 15 mg/kg per day for obese patients, given in 2 divided doses during meals.
Adverse Reactions
The toxicity and side effects of this product are less than those of chenodeoxycholic acid. It generally does not cause diarrhea. Other occasional adverse reactions include constipation, allergies, headaches, dizziness, pancreatitis, and tachycardia. During the treatment period, it may cause calcification of gallstones and soft stools.
Precautions
Acute biliary infection, biliary obstruction, pregnant and lactating women.
Special Population Medication
Precautions for children: Not clear. Precautions for pregnancy and lactation: Contraindicated for pregnant and lactating women. Precautions for the elderly: Use with caution in elderly patients.
Drug Interactions
Ursodeoxycholic acid capsules should not be taken at the same time as drugs such as cholestyramine (cholestyramine), colestipol (colestipol), aluminum hydroxide and/or aluminum hydroxide-magnesium trisilicate, because these drugs can bind to ursodeoxycholic acid in the intestine, thereby hindering absorption and affecting efficacy. If the above drugs must be taken, ursodeoxycholic acid capsules should be taken two hours before or two hours after taking the drug. Ursodeoxycholic acid capsules can increase the absorption of cyclosporine in the intestine. Patients taking cyclosporine should monitor the serum concentration of cyclosporine and adjust the dose of cyclosporine if necessary. In some cases, taking ursodeoxycholic acid capsules can reduce the absorption of ciprofloxacin.
Storage
Keep away from light and store in sealed container.
Packaging Specification
50mg
Validity Period
36 months
Manufacturer
Shanghai Hengshan Pharmaceutical Co., Ltd.
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Founded in:
1981-07-20 -
Address:
No. 176, Zidong Road, Minhang District, Shanghai -
Tax NO.:
91310112132628617W -
Registered Funds:
47.46 million yuan -
Website:
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Email: