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Isosorbide mononitrate extended-release tablets

Function and Efficacy

Isosorbide mononitrate can relax vascular smooth muscle and cause vasodilation. Its most important function is to dilate veins to reduce venous blood return, and also dilate systemic arteries and main coronary arteries, thereby reducing the preload and postload of the heart and promoting oxygen supply. At the same time, it can also improve blood supply to ischemic areas by promoting the redistribution of myocardial blood flow, thereby exerting an anti-myocardial ischemia effect.

Ingredients

The active ingredient is isosorbide mononitrate

Name Description Content CAS NO. Manufacturer
Isosorbide 5-mononitrateIngredients

It can relax vascular smooth muscle and cause vasodilation. Its most important function is to dilate veins to reduce venous blood return, and also dilate systemic arteries and main coronary arteries, thereby reducing the preload and postload of the heart and promoting oxygen supply. It can also improve blood supply to ischemic areas by promoting the redistribution of myocardial blood flow and play an anti-myocardial ischemia effect.

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16051-77-7 22

Appearance

Film-coated tablets are white or off-white after removing the coating.

Indication

It is used for long-term treatment of coronary heart disease, prevention of vasospastic and mixed angina pectoris, and is also suitable for treatment after myocardial infarction and long-term treatment of chronic heart failure.

Usage and Dosage

Take 30mg or 60mg every morning. Swallow the tablet with water. Do not crush or chew it.

Adverse Reactions

Cardiovascular system Common: hypotension, tachycardia. Central nervous system Common: headache, dizziness. Occasionally: syncope. Gastrointestinal tract Common: nausea. Occasionally: vomiting, diarrhea. Musculoskeletal system Very rare: myalgia. Skin Occasionally: rash, itching.

Precautions

It is contraindicated for patients with glaucoma, shock, significant hypotension, hypertrophic obstructive heart disease, acute myocardial infarction, severe cerebral arteriosclerosis, and those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.

Drug Interactions

Taking 5-type phosphodiesterase inhibitors at the same time will aggravate the vasodilatory effect of this product and may cause serious adverse reactions such as syncope and myocardial infarction. Therefore, 5-type phosphodiesterase inhibitors (such as sildenafil) should not be taken while taking this product.

Storage

Keep in a sealed container and away from light. Valid for 30 months.

Packaging Specification

40mg

Validity Period

24 months

Manufacturer

Shandong LINUO Pharmaceutical Company Limited

  • Founded in:

    2002-05-14
  • Address:

    No. 30766, Jingshi East Road, Jinan City
  • Tax NO.:

    91370100739258448G
  • Registered Funds:

    300 million yuan
  • Website:

  • Email:

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