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Cefmetazole Sodium for Injection

Function and Efficacy

None

Ingredients

Cefmetazole Sodium

Name Description Content CAS NO. Manufacturer
Cefmetazole sodiumIngredients

None

More
56796-39-5 14

Indication

The following infections caused by bacteria sensitive to this product among Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Proteus (indole-positive and -negative), Bacteroides, Peptococcus and Peptostreptococcus: septicemia; bronchitis, bronchiectasis infection, pneumonia, secondary infection of chronic respiratory diseases, pulmonary suppuration (lung abscess), empyema; cholangitis, cholecystitis; peritonitis; pyelonephritis, cystitis; Bartholinitis, intrauterine infection, adnexitis, parametritis; cellulitis around the jaws, jaw inflammation.

Usage and Dosage

Usually for adults, 1-2 grams (titer) per day, divided into 2 intravenous injections or intravenous drips. Usually for children, 25-100 mg (titer)/kg body weight per day, divided into 2-4 intravenous injections or intravenous drips. In addition, for refractory or severe infections, the daily dose can be increased to 4 grams (titer) for adults and 150 mg (titer)/kg body weight for children according to symptoms, and administered in 2-4 doses. For intravenous injection, 1 gram (titer) of this agent is dissolved in 10 ml of sterile water for injection, normal saline or glucose injection, and injected slowly. In addition, this agent can be added to the rehydration for intravenous drip. When dissolving the intravenous drip agent (100 ml bottle), do not use distilled water for injection (because the solution is not isotonic).

Adverse Reactions

1. Shock (less than 0.01%): Shock may occur (initial symptoms: discomfort, abnormal sensation in the mouth, wheezing, dizziness, urge to defecate, tinnitus, sweating, etc.), so it is necessary to observe carefully. If abnormalities occur, the drug should be discontinued and treated appropriately. 2. Acute renal failure (unknown incidence): Occasionally, severe renal damage such as acute renal failure may occur, so regular examinations should be performed and observations should be observed. If BUN and blood creatinine increase, the drug should be discontinued and treated appropriately. .3. Agranulocytosis (unknown incidence) and hemolytic anemia (unknown incidence): Agranulocytosis and hemolytic anemia may occur, so regular examinations should be performed and observations should be observed. If abnormalities occur, the drug should be discontinued and treated appropriately. .4. Pseudomembranous colitis (less than 0.01%): Occasionally, severe colitis such as pseudomembranous colitis with bloody stools may occur (initial symptoms: abdominal pain, frequent diarrhea), so it is necessary to observe carefully. If abnormalities occur, the drug should be discontinued and treated appropriately. .5. Interstitial pneumonia (unknown incidence) and PIE syndrome (unknown incidence): Interstitial pneumonia and PIE syndrome with fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, etc., if such symptoms occur, the drug should be discontinued immediately and appropriate treatment such as adrenocortical hormone preparations should be given. .6. Other side effects Mucocutaneous and ocular syndrome: Mucocutaneous and ocular syndrome (Stenens-Johnson syndrome) has been reported with other cephem antibiotics.

Precautions

1. Patients with a history of shock due to the ingredients of this drug are prohibited from using this drug. Patients with a history of allergy to the ingredients of this drug or cephem antibiotics should use this drug with caution. 2. Elderly patients should pay attention to the following contents, dosage and dosing interval, and observe the patient's condition and administer the drug with caution: (1) Elderly patients often have reduced physiological functions and are prone to side effects; (2) Elderly patients may have a tendency to bleed due to vitamin K deficiency.

Special Population Medication

Precautions during pregnancy and lactation: Use with caution in women who are pregnant or may become pregnant.

Drug Interactions

None

Storage

Store at room temperature.

Packaging Specification

2.0g (calculated as C15H17N7O5S3)

Manufacturer

Zhengzhou Yugang Star Pharmaceutical Co., Ltd.

  • Founded in:

    2017-11-08
  • Address:

    South side of Chunqiu Road, Guandu Industrial Park, Zhongmou County, Zhengzhou
  • Tax NO.:

    91410122MA44K1D7XY
  • Registered Funds:

    7.93 million yuan
  • Email:

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