Lomerizine Hydrochloride Capsules
Function and Efficacy
Pharmacological studies have shown that this product is a Ca2 antagonist with high selectivity for cerebral blood vessels. It blocks the influx of Ca2 in brain cells, inhibits the contraction of vascular smooth muscles, increases cerebral blood flow, and has a neuroprotective effect, protecting the brain from damage caused by ischemia, reperfusion, and hypoxia. In addition, this product can non-competitively inhibit the contraction of brain and peripheral arterial vessels induced by K, PGF2alpha, and 5-hydroxytryptamine, and inhibit neuroinflammation such as plasma protein exudation caused by trigeminal nerve stimulation, thereby preventing the occurrence of migraine and having a preventive and therapeutic effect on migraine.
Ingredients
The main ingredient is Lomerizine hydrochloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Lomerizine hydrochlorideIngredients |
Ca2 antagonists are highly selective for cerebral blood vessels. They inhibit the contraction of vascular smooth muscles and increase cerebral blood flow by blocking the influx of Ca2 in brain cells. They also have a neuroprotective effect, protecting the brain from damage caused by ischemia, reperfusion and hypoxia. They can non-competitively inhibit the contraction of cerebral and peripheral arterial vessels induced by K, PGF2alpha and 5-hydroxytryptamine, and inhibit neuroinflammation such as plasma protein exudation caused by trigeminal nerve stimulation, thereby preventing the occurrence of migraines and having a preventive and therapeutic effect on migraines. More |
101477-54-7 | 9 |
Appearance
This product is a hard capsule, the contents are white powder and granules.
Indication
This product is suitable for the prevention and treatment of migraine.
Usage and Dosage
Orally, take after breakfast and dinner or before bedtime, 5 mg of lomerizine hydrochloride each time, twice a day.
Adverse Reactions
Drowsiness, dizziness, nausea, fever, loss of appetite, increased GOT, GPT, gamma-GTP, LDH, etc. The incidence of side effects is low, the toxicity is low, and the tolerance is good.
Precautions
1. It is contraindicated for patients with a history of allergic reaction to this product; 2. It is contraindicated for patients in the acute stage of cerebral infarction, intracranial hemorrhage or with coagulation tendency; 3. It is contraindicated for pregnant women or women who may become pregnant.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
Concomitant use of antihypertensive drugs may cause enhanced interactions and appropriate treatment should be adopted.
Storage
Keep in a sealed container and away from light. Validity period: two years.
Packaging Specification
5mg
Validity Period
36 months
Manufacturer
Kun Shan Rotam Reddy Pharmaceutical Co., Ltd.
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Founded in:
1993-12-31 -
Address:
No. 2158 Huangpujiang Middle Road, Kunshan Development Zone, Jiangsu Province -
Tax NO.:
91320583608278334C -
Registered Funds:
$25,416,780 -
Website:
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Email: