Cefpodoxime Proxetil Tablets

The main ingredient of this product is cefpodoxime axetil. Chemical name: (6R, 7R)-7-[2-(2-amino-4-thiazolyl)-(Z)-2-(methoxyimino)acetamido]-3-methoxymethyl-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid-1-(isopropyloxycarbonyloxy)ethyl ester.

This product is a film-coated tablet, which appears off-white or light yellow after removing the film coating.

Generally, adults take 0.1g (2 tablets at a time) orally twice a day after meals. In addition, the dosage should be increased or decreased according to age and symptoms. For patients with severe symptoms or poor results, the dosage can be increased to 0.2g (4 tablets at a time) orally twice a day after meals.

1. Serious adverse reactions of this product: (1) Shock: It may occasionally cause symptoms of shock. You should pay attention to observation. If you experience discomfort, abnormal sensation in the mouth, wheezing, dizziness, urge to defecate, tinnitus, sweating, etc., you should stop taking the drug. (2) Skin mucosal eye syndrome, toxic epidermal necrolysis: Skin mucosal eye syndrome (Stevens-Johnson syndrome) and toxic epidermal necrolysis (Lyell syndrome) may occur occasionally. You should pay attention to observation. If any abnormality occurs, you should stop taking the drug and deal with it appropriately. (3) Pseudomembranous colitis: Severe colitis such as pseudomembranous colitis accompanied by bloody stools may occur occasionally. If abdominal pain or frequent diarrhea occurs, you should stop taking the drug immediately and give appropriate treatment. 2. Serious adverse reactions that similar drugs may cause: (1) Pancytopenia, agranulocytosis,

1. Patients who are allergic to penicillin or β-lactam antibiotics are contraindicated. 2. Patients who are allergic to cefpodoxime are contraindicated.

Precautions for children: Safety and efficacy data for infants under 5 months old have not been established. Precautions for pregnancy and lactation: Although there is no experimental evidence that cefpodoxime proxetil affects embryo formation or teratogenesis, like all drugs, it should be used with caution in the first few months of pregnancy. Cefpodoxime proxetil can be secreted from human breast milk. To avoid adverse reactions in breastfeeding infants, breastfeeding women should stop breastfeeding or switch to other drugs. Precautions for the elderly: The pharmacokinetic parameters of cefpodoxime proxetil are not affected by age, but the distribution of patients with renal insufficiency is changed, the elimination half-life is extended by 1.5 to 2 hours, and the plasma clearance rate and renal clearance rate are reduced. Therefore, patients with moderate to severe renal insufficiency (creatinine clearance 50ml/min) can reduce the dose by 50% or take the drug once a day.

1. Antacids or H2 receptor antagonists can reduce its absorption and lower its peak blood concentration; 2. Probenecid can increase its plasma concentration level.

seal.

0.1g*6s

24 months

Sichuan Hexin Pharmaceutical Co., Ltd.

• Founded in:

  2002-11-08

• Address:

  No. 12, Wuke East 3rd Road, Chengdu

• Tax NO.:

  91510100743617685C

• Registered Funds:

  19.3 million yuan

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