Oxytocin for injection

This product is a polypeptide hormone uterine contraction drug. 1. It stimulates the contraction of uterine smooth muscles, simulates the uterine contraction effect of normal delivery, causes the cervix to dilate, and the uterus's response to oxytocin gradually increases during pregnancy, reaching a peak at full term. 2. It stimulates the contraction of mammary smooth muscles, helps milk to be discharged from the breast, but does not increase the amount of milk secretion of the mammary gland.

The main ingredient of this product is oxytocin. Structural formula: This product is a peptide chain composed of 9 amino acids containing a disulfide bond. H-Cys-Tyr-Ile-Glu(NH2)-Asp(NH2)-Cys-Pro-Leu-Gly-NH2.

It is white or off-white freeze-dried block or powder.

Used for inducing labor, accelerating labor, and treating uterine bleeding caused by weak or poor uterine contractions after delivery and abortion; understanding the placental reserve function (oxytocin stimulation test).

1. Inducing or accelerating labor, intravenous drip, 2.5 to 5 units at a time, diluted with sodium chloride injection to contain 0.01 units per 1 ml. At the beginning of intravenous drip, no more than 0.001 to 0.002 units per minute, increase by 0.001 to 0.002 units every 15 to 30 minutes until uterine contractions are similar to those during normal labor, and the fastest is no more than 0.02 units per minute, usually 0.002 to 0.005 units per minute. 2. Control postpartum bleeding, intravenous drip 0.02 to 0.04 units per minute, and 5 to 10 units can be injected intramuscularly after the placenta is expelled.

Occasionally, nausea, vomiting, increased heart rate or arrhythmia may occur. High doses may cause high blood pressure or water retention.

The pelvis is too narrow, the birth canal is blocked, there is obvious cephalopelvic disproportion and abnormal fetal position, there is a history of caesarean section, a history of myomectomy, umbilical cord presentation or prolapse, placenta previa, fetal distress, strong uterine contractions, uterine atony that is not responsive to long-term medication, antepartum hemorrhage (including placental abruption), multiple pregnancy, an enlarged uterus (including polyhydramnios), and severe pregnancy-induced hypertension syndrome.

1. When cyclopropane and other hydrocarbons are inhaled for general anesthesia, the use of oxytocin can cause hypotension, sinus bradycardia or (and) atrioventricular arrhythmia in the parturient. When enflurane concentrations of 1.5% and halothane concentrations of 1.0% are inhaled for general anesthesia, the effect of the uterus on oxytocin is weakened. Enflurane concentrations of 3.0% can eliminate the reaction and may cause uterine bleeding. 2. When other uterotonic drugs are used simultaneously with oxytocin, the uterine tension may be too high, resulting in uterine rupture or (and) cervical tearing.

Keep tightly closed in a cool, dark place.

10 units

Nanjing Xinbai Pharmaceutical Co., Ltd.

• Founded in:

  2001-03-28

• Address:

  No. 68, Xingang Avenue, Nanjing Economic and Technological Development Zone

• Tax NO.:

  91320192726088531G

• Registered Funds:

  147.85 million yuan

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