Nefopam Hydrochloride Injection
Function and Efficacy
This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. The chemical structure belongs to cyclized o-methylbenzylamine. Therefore, it does not have the characteristics of non-steroidal anti-inflammatory drugs, nor is it an opioid receptor agonist. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no inhibitory effect on the circulatory system. There is no tolerance and dependence. Acute toxicity LD50 (mg/kg): mice, oral 66.6; intraperitoneal 28.7; intravenous 21.9. Rats, oral 178; intramuscular injection 56.9.
Ingredients
Nefopam Hydrochloride
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Nefopam hydrochlorideIngredients |
This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. Its chemical structure belongs to cyclized o-methylbenzylamine. Therefore, it does not have the characteristics of non-steroidal anti-inflammatory drugs, nor is it an opioid receptor agonist. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no depressant effect on the circulatory system. There is no tolerance and dependence. More |
23327-57-3 | 12 |
Appearance
This product is a colorless clear liquid.
Indication
It is used for postoperative analgesia, cancer pain, acute traumatic pain. It is also used for visceral smooth muscle colic such as acute gastritis, biliary ascariasis, ureteral stones, etc. It is also used as an auxiliary drug for local anesthesia, acupuncture anesthesia, etc.
Usage and Dosage
Intramuscular or intravenous injection: 20 mg at a time, or every 3 to 4 hours if necessary.
Adverse Reactions
When the effects occur, there are often drowsiness, nausea, sweating, dizziness, headache, etc. But it usually does not last long. Occasionally, dry mouth, dizziness, and rash are seen.
Precautions
It is contraindicated in patients with severe cardiovascular disease, myocardial infarction or convulsions.
Special Population Medication
Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
1ml:20mg
Validity Period
24 months
Manufacturer
Sinopharm Ronshyn Pharmaceutical Co., Ltd.
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Founded in:
1999-05-06 -
Address:
No. 686, Yingbin Avenue, Wuzhi County, Jiaozuo City, Henan Province -
Tax NO.:
914108237156088969 -
Registered Funds:
150 million yuan -
Email: