Granisetron Hydrochloride and Sodium Chloride Injection

1. This product is a highly selective 5HT3 receptor antagonist; 2. It has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery; 3. Mechanism of action: factors such as radiotherapy, chemotherapy and surgery can cause enterochromaffin cells to release 5HTTrarr; 5HT can activate the 5HT3 receptors of the central nervous system or vagus nerve and cause vomiting reflexrarr; Granisetron hydrochloride antagonizes the 5HT3 receptors of the central chemoreceptor area and peripheral vagus nerve endingsrarr; inhibits the occurrence of nausea and vomiting; 4. This product has high selectivity and has no side effects such as extrapyramidal reactions and excessive sedation.

Main ingredients: Granisetron hydrochloride

This product is a colorless or almost colorless clear liquid.

Used for nausea and vomiting caused by radiotherapy and cytotoxic chemotherapy.

For intravenous drip, the adult dose is usually 3 mg, given 30 minutes before treatment. Most patients only need to take the drug once, and the preventive effect on nausea and vomiting can last for more than 24 hours. If necessary, the dose can be increased by 1-2 times, but the maximum daily dose should not exceed 9 mg.

Common side effects include headache, fatigue, fever, constipation, and occasional transient asymptomatic increase in liver transaminases. The reaction is mild and can be recovered without special treatment.

1. It is contraindicated for patients with gastrointestinal obstruction. 2. It is contraindicated for patients who are allergic to this product.

Precautions for children: The safety of the drug for children has not been determined, so this product is contraindicated. Precautions for pregnancy and lactation: Pregnant women should not use it unless necessary. Lactating women should use it with caution. If you use this drug, you should stop breastfeeding. Precautions for the elderly: No dosage adjustment is required for the elderly.

This trial was not conducted and no references are available.

Keep in a light-proof and airtight container.

50ml: Granisetron 3mg and sodium chloride 0.45g

18 months

Chengdu Brilliant Pharmaceutical Co., Ltd.

• Founded in:

  1995-10-10

• Address:

  No. 263, Hexiang 3rd Street, Chengdu Hi-tech Zone

• Tax NO.:

  91510100633104205M

• Registered Funds:

  450 million yuan

• Website:

  Log in to view

• Email:

  Log in to view