Pirenoxine sodium eye drops
Function and Efficacy
Studies have shown that one of the causes of cataract formation is that soluble proteins in the lens are gradually transformed into insoluble proteins by the action of quinones. Quinones are formed by the abnormal metabolism of tryptophan, an important functional amino acid in the body. The effect of such quinones on soluble proteins in the lens can be competitively inhibited by pyrenoxetine sodium. In addition, pyrenoxetine sodium can also fight against cataracts caused by free radical damage to the lens. Therefore, this product has a certain inhibitory effect on the development of cataracts. Animal experiments have shown that pyrenoxetine sodium can reduce the incidence of posterior capsule opacity after extracapsular cataract extraction.
Ingredients
Main ingredient: Sodium pyrenoxine Chemical name: 1-hydroxy-5-oxo-5H-pyrido-[3,2-?]-phenoxazine-3-carboxylic acid; molecular formula and molecular weight: C16H18N2O5, 308.25.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| 1-HYDROXY-5-OXO-5H-PYRIDO[3,2-A]PHENOXAZINE-3-CARBOXYLIC ACID MONOSODIUM SALTIngredients |
Pirenoxine sodium can competitively inhibit the effects of quinone substances on lens soluble proteins, and can also counteract the damage of free radicals to the lens, thus having a certain inhibitory effect on the development of cataracts; animal experiments have shown that pirenoxine sodium can reduce the incidence of posterior capsule opacity after extracapsular cataract extraction. More |
51410-30-1 | 6 |
Appearance
This product is light yellow or orange-yellow liquid.
Indication
It is mainly used to treat early senile cataracts, mild diabetic cataracts or complicated cataracts.
Usage and Dosage
Eye drops: 1-2 drops at a time, 3-4 times a day.
Adverse Reactions
A very small number of patients may experience mild eye irritation.
Precautions
Do not use in case of eye injury or severe infection, or follow doctor's advice.
Special Population Medication
Precautions for children: There is a lack of systematic research data on its use in children, and there is a lack of data on its use in infants under 2 years old. Therefore, this product should not be used in children under 2 years old. It is also not suitable for children over 2 years old. If there is an indication for its use, it is necessary to weigh the pros and cons before deciding whether to use it. Precautions for pregnancy and lactation: This product can pass through the blood-placental barrier. Animal experiments have shown that this product can cause teratogenesis, such as syndactyly, oligodactyly, and dystocia in rats. Data from the US FDA shows that the use of this drug in pregnant women is Class C, which means that it is toxic in animal experimental studies and there is a lack of sufficient data on human studies. Therefore, pregnant women should avoid using it. This product can be secreted into breast milk. No problems have been confirmed in the use of this product in humans, but this product can increase the possibility of kernicterus in newborns. When there is an indication for its use in lactating women, the pros and cons should be weighed before deciding whether to use it. Precautions for the elderly: Not yet clear
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
Keep away from light and stored in a sealed place.
Packaging Specification
15ml:0.8mg
Validity Period
24 months
Manufacturer
-
Founded in:
2003-12-18 -
Address:
No. 28, High-tech Industrial Park, Wuhan Economic and Technological Development Zone -
Tax NO.:
91420000757010980Y -
Registered Funds:
114 million yuan -
Website:
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Email: