Eperisone Hydrochloride Tablets

Literature data show that this product can act on the central nervous system and vascular smooth muscle at the same time, relieve skeletal muscle tension and improve blood flow. By improving various muscle tension symptoms, inhibiting spinal reflexes, and acting on the γ-system, reducing the sensitivity of muscle spindles, thereby relieving skeletal muscle tension, and by dilating blood vessels to improve blood flow, it blocks the vicious cycle of skeletal muscle tension from multiple aspects: hypertonicity → circulatory disorders → muscle pain → hypertonicity. No obvious toxic reactions were observed in the acute and long-term toxicity tests of this product. The oral LD50 of mice is 668.7 mg/kg, and the intravenous LD50 is 41.98 mg/kg. The experimental values are basically consistent with the literature values. The results of animal experiments show that this product has no antigenicity, no mutagenicity, no reproductive toxicity, and no physical or mental dependence.

EperisoneHCl, 4-ethyl-2-methyl-3-piperidinylpropiophenone hydrochloride, has a molecular formula of C17H25NO·HCl and a molecular weight of 295.85.

This product is white tablets.

Central muscle relaxant. 1. Used to improve the muscle tension of the following diseases: cervical back shoulder arm syndrome, frozen shoulder, low back pain; 2. Used to improve spastic paralysis caused by the following diseases: cerebrovascular disorder, spastic spinal cord paralysis, cervical spondylosis, surgical sequelae (including brain and spinal cord tumors), traumatic sequelae (spinal cord injury, head trauma), amyotrophic lateral sclerosis, infantile cerebral palsy, spinocerebellar degeneration, spinal vascular disorder, subacute spinal cord neurosis (SMON) and other brain and spinal cord diseases.

Orally after meals. Usually adults take 1 tablet 3 times a day. Or as directed by your doctor.

1. The medication should be discontinued when the following adverse reactions occur: shock, abnormal liver function, abnormal kidney function, abnormal blood test (including red blood cell count, hemoglobin value); 2. The following adverse reactions may occur: Skin: rash, itching, etc.; Mental and nervous system: insomnia, headache, drowsiness, body stiffness, numbness of limbs, decreased perception, tremor of limbs, etc.; Digestive system: nausea, vomiting, loss of appetite, stomach discomfort, dry mouth, constipation, diarrhea, abdominal pain, abdominal distension, etc., occasionally stomatitis; Urinary system: urinary retention, urinary incontinence, feeling of incomplete urination, etc.; Systemic symptoms: weakness in limbs, unstable standing, general fatigue, occasionally dizziness, decreased muscle tension, etc.; Others: facial heat, sweating, etc.

It is contraindicated for patients with severe liver and kidney dysfunction, accompanied by shock, and breastfeeding women.

Precautions for children: The safety of this product in children has not been established (lack of experience in use). Precautions for pregnancy and lactation: 1. Pregnant women should use with caution. 2. Breastfeeding women are prohibited. Precautions for the elderly: In general, the physiological functions of elderly patients are reduced, so measures such as reducing the dosage and strengthening observation should be taken.

There have been reports of ocular accommodation disorders when a similar drug, tolperisone hydrochloride, is used in combination with methoxycarbamol.

Store away from moisture after opening.

50mg

Tentative 36 months

Qingdao Guohai Biopharmaceutical Co., Ltd.

• Founded in:

  2010-01-04

• Address:

  No. 16 Fengjin Road, Chengyang District, Qingdao City, Shandong Province

• Tax NO.:

  91370214697187900G

• Registered Funds:

  68.1 million yuan

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