Sodium Chloride Injection for Blood Transfusion

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body, mainly present in extracellular fluid, and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the hypothalamus, posterior pituitary and kidneys to maintain the stability of body fluid volume and osmotic pressure.

The main ingredients of this product and its chemical name: Sodium chloride

This product is a colorless, clear liquid with a slightly salty taste.

Water loss due to various reasons, including hypotonic, isotonic and hypertonic water loss; hyperosmotic non-ketotic diabetic coma; hypochloremic metabolic alkalosis; external use of normal saline to rinse eyes and wash wounds, etc.; also used for water bag induction of labor in obstetrics.

1 Hypertonic dehydration During hypertonic dehydration, the osmotic concentration of the patient's brain cells and cerebrospinal fluid increases. If the treatment causes the sodium concentration and osmotic concentration of plasma and extracellular fluid to drop too quickly, cerebral edema may occur. Therefore, it is generally believed that within the first 48 hours of treatment, the plasma sodium concentration should not drop by more than 0.5mmol/L per hour. If the patient is in shock, 0.9% sodium chloride injection should be given first, and colloid should be supplemented as appropriate. When the shock is corrected, blood sodium>155mmol/L, and plasma osmotic concentration>350mOsm/L, 0.6% hypotonic sodium chloride injection can be given. When the plasma osmotic concentration is <330mOsm/L, 0.9% sodium chloride injection should be used instead. The total amount of fluid replacement is calculated according to the following formula for reference:

Generally there are no adverse reactions. Improper use may include: 1. Dosing too quickly or excessively can lead to high blood pressure, headache, and dizziness; 2. Weight gain and edema; 3. Accelerated heart rate, chest tightness, difficulty breathing, and wheezing in the lungs.

The following patients are contraindicated for use: (1) heart failure; (2) pulmonary edema; (3) cerebral edema, increased intracranial pressure; (4) ascites due to cirrhosis; (5) oliguria in acute renal failure; patients with chronic renal failure who do not respond well to diuretics; and (6) hypernatremia.

When used as a drug solvent or diluent, attention should be paid to the incompatibility between drugs. 1. When used with amphotericin B, it will cause turbidity, precipitation, or discoloration; 2. It is forbidden to use it with reserpine, polymyxin B sulfate, polymyxin E sulfate, and cephalosporin I.

Keep in a sealed container. Valid for two years.

250ml:2.25g

Sichuan Nigale BIOTECHNOLOGY Co., Ltd.

• Founded in:

  2013-06-08

• Address:

  No. 28, Kuixing Road, Dongxi Town, Jianyang City

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  91510185071405021T

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  13.510795 yuan

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