Captopril Tablets
Function and Efficacy
This product is a competitive angiotensin converting enzyme inhibitor, which prevents angiotensin I from being converted into angiotensin II, thereby reducing peripheral vascular resistance and reducing water and sodium retention by inhibiting aldosterone secretion. This product can also dilate peripheral blood vessels by interfering with the degradation of bradykinin. For patients with heart failure, this product can also reduce capillary wedge pressure and pulmonary vascular resistance, increase cardiac output and exercise tolerance time.
Ingredients
Captopril.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CaptoprilIngredients |
This product is a competitive angiotensin converting enzyme inhibitor, which prevents angiotensin I from being converted into angiotensin II, thereby reducing peripheral vascular resistance and reducing water and sodium retention by inhibiting aldosterone secretion. This product can also dilate peripheral blood vessels by interfering with the degradation of bradykinin. For patients with heart failure, this product can also reduce capillary wedge pressure and pulmonary vascular resistance, increase cardiac output and exercise tolerance time. More |
62571-86-2 | 28 |
Appearance
This product is a sugar-coated tablet, which appears white or off-white after removing the sugar coating.
Indication
1. Hypertension. 2. Heart failure.
Usage and Dosage
Depending on the condition or individual differences, this product should be taken under the guidance or supervision of a physician. The dosage should follow the principle of individualization and be adjusted according to the efficacy. 1. Common dosage for adults: (1) For hypertension, take 12.5 mg orally once, 2-3 times a day. Increase to 50 mg 2-3 times a day within 1-2 weeks as needed. If the efficacy is still unsatisfactory, other antihypertensive drugs can be added. (2) For heart failure, start with 12.5 mg orally once, 2-3 times a day. If necessary, gradually increase to 50 mg 2-3 times a day. If further increase is needed, observe the efficacy for 2 weeks before considering it. For patients who have recently taken a large amount of diuretics, are in the state of hyponatremia and hypovolemia, and have normal or low blood pressure, the initial dose should be 6.25 mg 3 times a day, and then gradually increase to the common dosage through testing. 2. Common dosage for children: For both antihypertensive and heart failure treatment, start with 0.3 mg/kg of body weight, 3 times a day. If necessary, increase by 0.3 mg/kg every 8-24 hours to obtain the lowest effective dose.
Precautions
Patients who are allergic to this product or other angiotensin-converting enzyme inhibitors are contraindicated.
Special Population Medication
Precautions for children: There have been reports that this product can cause excessive and persistent decreases in blood pressure in infants, accompanied by oliguria and convulsions, so the use of this product is limited to those who have not responded to other antihypertensive treatments. Precautions for pregnancy and lactation: 1. This product can pass through the placenta. 2. This product can be excreted into breast milk, and its concentration is about 1% of the maternal blood drug concentration, so lactating women must weigh the pros and cons when using it. 3. Pregnant women who absorb ACEⅠ can affect fetal development and even cause fetal death, so pregnant women are prohibited from using it. Precautions for the elderly: The elderly are more sensitive to antihypertensive effects, so the dosage of this product should be reduced as appropriate.
Storage
Keep in a light-proof and airtight container.
Packaging Specification
25㎎
Validity Period
36 months.
Manufacturer
Shijiazhuang Kedi Pharmaceutical Co., Ltd.
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Founded in:
1998-04-13 -
Address:
No. 366 Xinshi North Road -
Tax NO.:
91130101601026863C -
Registered Funds:
40 million yuan -
Website:
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Email: