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Gliclazide Tablets

Function and Efficacy

This product is a second-generation sulfonylurea hypoglycemic drug with a strong effect. Its mechanism is to selectively act on pancreatic islet cells to promote insulin secretion and increase insulin release after eating glucose, so that the production and output of glycogen are inhibited. Animal experiments and clinical use have proven that this product can reduce platelet aggregation and adhesion, and help prevent and treat diabetic microangiopathy.

Ingredients

This product contains 80 mg of gliclazide.

Name Description Content CAS NO. Manufacturer
GliclazideIngredients

The second-generation sulfonylurea hypoglycemic drugs selectively act on pancreatic islet cells, promote insulin secretion and increase insulin release after ingesting glucose, inhibit liver glucose production and output; reduce platelet aggregation and adhesion, and help prevent and treat diabetic microangiopathy.

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21187-98-4 23

Appearance

White flakes.

Indication

Used for type 2 diabetes, adult-onset diabetes, diabetes with obesity or with vascular disease.

Usage and Dosage

Oral administration: the initial dosage is 40-80 mg (0.5-1 tablet), 1-2 times a day, and then adjusted to 80 mg-240 mg (1-3 tablets) a day according to blood sugar level, taken in 2-3 times. After blood sugar is controlled, change to a maintenance dose. Elderly people can take less.

Adverse Reactions

Occasionally, there may be mild nausea, vomiting, upper abdominal pain, constipation, diarrhea, erythema, urticaria, thrombocytopenia, granulocytopenia, anemia, etc. Most of them disappear after stopping the drug.

Precautions

Use with caution in pregnant and lactating women. Contraindicated in patients with severe liver or kidney failure.

Special Population Medication

Precautions for children: Not clear yet. Precautions for pregnancy and lactation: Animal experiments and clinical observations have shown that sulfonylurea hypoglycemic drugs can cause teratogenesis and are excreted through breast milk, so pregnant women and nursing mothers should not use them. Precautions for the elderly: The dosage should be appropriately reduced.

Drug Interactions

When used in combination with non-steroidal anti-inflammatory drugs (especially salicylates), sulfonamide antibiotics, coumarin anticoagulants, monoamine oxidase inhibitors, β-receptor blockers, benzodiazepines, tetracycline, chloramphenicol, dicyclohexine, clofibrate, ethanol and other drugs, the dosage should be reduced to avoid hypoglycemia.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

80mg

Validity Period

18 months

Manufacturer

Shanghai Shyndec Pharmaceutical Co., Ltd.

  • Founded in:

    1996-11-27
  • Address:

    No. 378, Jianlu Road, Pudong New Area, Shanghai
  • Tax NO.:

    91310000630459924R
  • Registered Funds:

    1,341,172,692 yuan
  • Website:

  • Email:

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