Vicriviroc Malate
541503-81-5
99%
2026-06-30
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Vicriviroc Malate Cat No CEI-0332 Description Vicriviroc Malate CAS No "541503-81-5 Molecular Weight 667.72 Purity >99% Storage 2 years at -20 centigrade Targets CCR5 Molecular Formula C28H38F3N5O2.C4H6O5 Solubility No In vitro Vicriviroc is nearly 6-fold less active than SCH-C (IC50 = 5.8 uM versus 1.1 uM) in attenuating hERG current among voltage-clamped L929 cells, indicating a reduced potential for cardiac effects. Vicriviroc inhibits MIP-1alpha induced migration of Ba/F3 cells stably expressing recombinant human CCR5, with IC50 of 0.91 nM. Vicriviroc is also highly active against a Clade G Russian isolate RU570 with EC90 of 16 nM, which is resistant to inhibition by SCH-C (EC90 > 1 uM). Vicriviroc could target an early step in the viral life cycle prior to reverse transcription and virion maturation, the targets of reverse transcriptase inhibitor and protease inhibitor, respectively. cas_num 541503-81-5 category Specialty Chemicals(c26) Basic Info-
Product Name:
(4,6-Dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone;2-hydroxybutanedioic acid
Other Name:Vicriviroc Malate;541503-81-5;(4,6-Dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone malate;DTXSID50436815;EX-A199;MFCD14635362;C28H38F3N5O2.C4H6O5;AC-31387;AS-19361;X5032
CAS No.:541503-81-5
Molecular Formula:C32H44F3N5O7
InChIKeys:HQJIGHNTROUVLT-RIAYWLAYSA-N
Molecular Weight:667.7
Exact Mass:667.31928325
DSSTox ID:DTXSID50436815
Categories:
Characteristics -
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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