Lovastatin
2 Inquiries
75330-75-5
98%
2026-07-11
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Lovastatin Cat No CEI-0528 Description A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Alias Mevinolin; Mevacor; Monacolin K; 6-α-Methylcompactin; MK-803 Appearance Beige solid Product Overview A HMG-CoA inhibitor CAS No 75330-75-5 Molecular Weight 347.39 Purity >98% Storage -20 centigrade Synonyms Mevinolin; Mevacor; Monacolin K; 6-α-Methylcompactin; MK-803 Targets HMG-CoA Molecular Formula C₂₄H₃₆O₅ Solubility DMSO (50 mM) Shipping Conditions Gel pack category Circulatory System Drugs(c1427) cas_num 75330-75-5 Basic Info-
Product Name:
Lovastatin
Other Name:SiMvastatin EP IMpurity E;Lovastatin,Monacolin K;8-[2-(4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-nap;6alpha-Methylcompactin Mevinolin Monacolin K;)ethyl]-1-naphthalenylester;[1s-[1alpha(r*),3alpha,7beta,8beta(2s*,4s*),8abeta]]-2-methylbutanoicacid1,2,;1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobuty;2-methyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-butanoicaci
CAS No.:75330-75-5
Molecular Formula:C24H36O5
InChIKeys:PCZOHLXUXFIOCF-BXMDZJJMSA-N
Molecular Weight:404.54
Exact Mass:404.54
EC Number:616-212-7
Color/Form:White
HScode:29322090
Categories:
Characteristics-
PSA:
72.8
Physical Properties:Appearance: White, nonhygroscopic crystalline powder. Solubility: Insoluble in water (0.0004mg/mL); sparingly soluble in ethanol, methanol, isobutanol, isopropanol, acetonitrile, n-propanol; soluble in acetone, N-dimethylformamide; freely soluble in chloroform. Melting point: 174.5°C. Specific optical rotation: 25°C for D (sodium) line, +323° (concentration 0.5 g in 100 ml acetonitrile). Stability: Lovastatin is sensitive to light. Following exposure to extreme light conditions, the drug is stable for 24h or 1month when exposed to UV (approximately 3230 lux) or fluorescent (approximately 10,764 lux) light, respectively, at 28°C in air.
XLogP3:4.08
Appearance:Solid
Density:1.12±0.1 g/cm3(Predicted)
Melting Point:175°C
Boiling Point:559.2±50.0 °C(Predicted)
Flash Point:185.3±23.6 °C
Refractive Index:320 ° (C=0.5, CH3CN)
Water Solubility:0.0004 mg/mL at 25 ºC
Storage Conditions:2-8°C
Vapor Pressure:0Pa at 25℃
Toxicity:LD50 orally in mice: >1000 mg/kg (Endo)
Specific rotation:D25 +323° (c = 0.5 g in 100 ml acetonitrile)
PKA:13.49±0.40(Predicted)
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Lovastatin
1 KG Jun 28, 2024
United States
Red yeast rice
1 KG Apr 21, 2026 Post an enquiry for this product
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