Geldanamycin
30562-34-6
95%
2026-07-05
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Geldanamycin Cat No CEI-1022 Description Geldanamycin is an antibiotic and a potent antitumor compound. It inhibits pp60src tyrosine kinase, and it also binds specifically to heat shock protein Hsp90 and its GP96 homologue. It is known to inhibit protein maturation. Abbr Geldanamycin(pp60src tyrosine kinase, HSP90AA1, HSP90B1) Alias EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, LAP2 Appearance Yellow crystalline solid; granular or powder. CAS No 30562-34-6 Molecular Weight 560.64 Purity > 95% Storage Store at or below -20 centigrade. Due to reactivity, it is unstable in water and ethanol. Does not react with DMSO, but DMSO can contain moisture from the air and/or small amounts of DMSO degradation products that might react. Keep DMSO stock solutions out of contact with air. Synonyms EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, LAP2 Targets pp60src tyrosine kinase, Hsp90, GP96 IC50 20 nM Molecular Formula C29H40N2O9 category Antibiotics(c1416) cas_num 30562-34-6 Basic Info-
Product Name:
Geldanamycin
Other Name:Geldanamycin;2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-,9-carbamate;2-Azabicyclo[16.3.1]docosane,geldanamycin deriv.;2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9-[(aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-,[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-;[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-9-[(Aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione;NSC 122750;NSC 212518;(+)-Geldanamycin;(8S,9S,12S,13R,14S,16R)-13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate;31828-93-0;150575-55-6;1807916-57-9;1955474-12-0
CAS No.:30562-34-6
Molecular Formula:C29H40N2O9
InChIKeys:InChIKey=QTQAWLPCGQOSGP-KSRBKZBZSA-N
Molecular Weight:560.64
Exact Mass:560.64
DSSTox ID:DTXSID7042691
HScode:2933990090
Categories:
Characteristics-
PSA:
164
XLogP3:3.43750
Appearance:yellow to orange powder
Density:1.2±0.1 g/cm3
Melting Point:252-255 °C
Boiling Point:783.9°C at 760 mmHg
Flash Point:87℃
Refractive Index:1.559
Water Solubility:DMSO: soluble
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product