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52853-40-4 | ChemExpress buy - large image1
52853-40-4 | ChemExpress buy - image1

52853-40-4 | ChemExpress

Unit Price: Get Latest Price
CAS No.:

52853-40-4

Port:

shanghai

Packaging:

10 kg

Price valid (until):

2024-04-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

CRO

  • Product Description

  • Seller Information

  • Description

    6-(Bromomethyl)pteridine-2,4-diamine hydrobromide

    Intermediate of Pralatrexate for the treatment of T-cell lymphoma
    We can provide high-quality 6-(Bromomethyl)pteridine-2,4-diamine hydrobromide and its derived impurities.


    Brand:ChemExpress
    CAS:52853-40-4
    Catalog_No:HY-32180
    Molecular Formular:C7H8Br2N6
    Molecular Weight:335.99


    Contact:
    TEL:+1-970-439-2030 (USA)、+86 (21) 5895-0125 (Global)
    Email:info@chemexpress.com



    Brand Introduction:
    ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.


    ChemExpress Services:
     
    Drug Discovery: synthetic chemistry; medicine chemistry; FTE/FFS services.

    Process Development: APIs and intermediates development; formulation development.

    New Modalities Development: ADC; peptide; oligonucleotide and so on.

    Manufactory: support production from milligrams to kilograms, both with GMP and non-GMP capabilities.

    Analytical Development & Quality Control: R&D testing; stability study; genotoxic impurity research and so on.

    Regulatory CMC Support

    Eany development services in Synthetic Chemistny:Providing serices related to high qualty compound synthesis,chemical custom synthesis and analytical chemistry.

    Pharmaceutical Chemistry eaniy development services: including high-throughput screening, drug synthesis, seding compounds, lead compounds, and IND fling support.

    Process development: Covers AP! & intermediates process development, validation, transfer, and formulation development.

    Commerial producion:it hasa research and development base forthe producion otapis intermediates and prenarations and provdes commeria prouction semices.

    CMC services: Provide one-stop CMC services, from lND to NDA stage of pharmaceutical research and development and dedlaration services, accelerate IND declaration.

    ADC drug and highly active drug development and production:  Provides a one-stop CRO & CDMO service for the small molecule aspect of ADC drugs, as well as customized ADC conjugation services. 

    Oligonucleotide drug process development and production: Provide oligonucleotide customized products and services to meet different needs.

    Analytical testing services and quality control: Provide integrated analytical testing services and drug quality research support

    ChemExpress committed to being a steadfast companion for our clients, gaining profound insight into their needs. Our focus is on accelerating the empowerment of global partners across the full spectrum, from preclinical stages to commercial production. This commitment aims for more streamlined drug development, swifter market entry, and an earlier positive impact on human health.


    Product details:https://www.chemexpress.com/product/HY-32180

    Basic Info
    Product Name:

    6-BROMOMETHYL-PTERIDINE-2,4-DIAMINE HBR

    Other Name:

    2,4-pteridinediaMine, 6-(broMoMethyl)-, hydrobroMide;2, 4-diaMino-6-(broMoMethyl)-pteridine HCL;2,4-diamino-6-(bromomethyl)pteridine(for methotrexate);6-BROMOMETHYL-PTERIDINE-2,4-DIAMINE HBR;2,4-Diamino-6-(bromomethyl)pteridine Hydrobromide;6-(Bromomethyl)-2,4-diaminopteridine Hydrobromide;Nsc253943;6-Bromomethyl-pteridine-2,4-diamine hydrobromide

    CAS No.:

    52853-40-4

    Molecular Formula:

    C7H8Br2N6

    InChIKeys:

    KMQIBGKVZDBGAH-UHFFFAOYSA-N

    Molecular Weight:

    335.98662

    Exact Mass:

    333.917694

    EC Number:

    1308068-626-2

    NSC Number:

    253943

    HScode:

    2933990090

    Characteristics
    PSA:

    104

    XLogP3:

    2.59960

    Melting Point:

    >195°C (dec.)

    Boiling Point:

    524.7ºC at 760 mmHg

    Flash Point:

    271.1ºC

    Storage Conditions:

    -20°C Freezer

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    CRO

    Location:

    1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    3

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2006

    Company Profile

    Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

    Over the past 17 years, we have established a state-of-the-art QC/QA system aligning with ICH guidelines for pharmaceutical manufacturing. We provide our clients with high-quality products and CMC services across the entire life-cycle of drug development.


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