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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Nifedipine for Sale > Provide Pharmaceutical Nifedipine CAS 21829-25-4 99% Purity Powder 244-598-3
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Provide Pharmaceutical Nifedipine CAS 21829-25-4 99% Purity Powder 244-598-3

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Unit Price:

$50-65/G FOB

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CAS No.:

21829-25-4

Grade:

Medical Grade

Content:

99%

Port:

China Port

Brand:

TNJONE

Packaging:

1kg Per Bag, 25kg Per Drum or according to customer's detail requirement.

Price valid (until):

2028-02-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail 




    Product Introduction 

    Nifedipine, also known as 1, 4-dihydro-2, 6-dimethyl-4 -(2-nitrophenyl)-3, 5-pyridine dicarboxylate, is a dihydropyridine calcium antagonist used for the prevention and treatment of coronary heart disease angina pectoris, especially variant angina pectoris and angina pectoris caused by coronary artery spasms.It has no adverse effect on respiratory function, so it is suitable for patients with angina pectoris suffering from respiratory obstructive diseases, and its efficacy is better than that of β-receptor antagonists.It is also applicable to various types of hypertension, and has a good effect on intractable and severe hypertension.Because it can reduce afterload, it also has a good effect on refractory congestive heart failure, and is suitable for long-term use.

    Name of product :Nifedipine;Nifedipine powder;Nifedipine price;

    Nifedipine powder pure natural 99% White Powder cas 21829-25-4 Evergreen EGC-Nifedipine

    Active api pharmaceuticals Ingredients; api raw material pharma company suppliers; api raw material manufacturing companies


    What is Nifedipine?

    Nifedipine, also known as heartdine, Lixinpine, and nitrophenyridine, is a dihydropyridine calcium antagonist, which can inhibit the uptake of Ca2+ by myocardium and vascular smooth muscle, dilate coronary arteries, increase coronary blood flow, and improve myocardial tolerance to ischemia. Meanwhile, it can dilate peripheral arteriolas, reduce peripheral vascular resistance, relieve coronary spasm, and increase coronary flow. Improve myocardial hypoxia, thereby lowering blood pressure. Small dose dilation of coronary artery does not affect blood pressure, which is a good antiangina drug. Chemicalbook is used to prevent and treat angina pectoris of coronary heart disease. It has no adverse effect on respiratory function, especially for angina pectoris caused by coronary artery spasm and patients with respiratory obstructive diseases. 


    Applications:

    Treatment of intractable congestive heart failure can be long-term use of this product. Also used to treat primary pulmonary hypertension, diffuse esophageal spasm and bronchial asthma, duodenal ulcer, urinary tract obstruction , exercise asthma, achalasia and so on.
    Nifedipine has certain selectivity for vascular smooth muscle, and its direct negative inotropic and degenerative effects on the heart are weak. Therefore, systemic administration does not cause heart rate to slow down and manifests as increased heart rate reflex.
    1) Prevent calcium influx
    2) hinder the release of calcium in the cell wall
    3) Block α-adrenergic receptors on the vascular membrane
    4) Inhibit the activity of phosphodiesterase
    5) Interact with Calmodulin
    6) Activate Na+, K+, ATPase
    7) Activation of calcium ion pump
    3. Inhibition of platelet aggregation Nifedipine can inhibit the aggregation of human platelets induced by ADP and collagen at a concentration of 50 μg/mL.


    Prodcut name

    Nifedipine


    Synonyms  1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid Dimethyl Ester;Procardia XL;Fenihidine;4-(2'-nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridine;Corinfar;
    MOQ 1kg
    CAS 21829-25-4
    Appearance Powder
    Molecular Formula C17H18N2O6
    Molecular Weight 346.335
    Assay 99%
    Application Pharma grade
    Packing As per your request
    Storage Preserve in tight, light-resistant containers in a cool place
    Remarks NA
    Custom synthesis Available




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    • Provide Pharmaceutical Nifedipine  CAS 21829-25-4 99% Purity Powder 244-598-3 Certificates 1

    Basic Info
    Product Name:

    Nifedipine

    Other Name:

    3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-,dimethyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-,dimethyl ester;Nifedipine;BAY-a 1040;4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine;Adalat;BAY 1040;2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine;Corynphar;Corinfar;Procardia;Fenihidine;Glopir;TN 873R;Cordafen;2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester;Cordaflex;Niphedipine;Dimethyl 4-(o-Nitrophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate;Procardia XL;Nifelate;Sepamit R;Adalat CC;Nifelan;Nifedipine retard;UV-ENP 349PINA;Macorel;Duranifin;Adalat 10;Nifangin;Anpine;Dignokonstant;Zenusin;Adalat LA;Nifedipres;Adalat GITS 30;Fedcor Retard;Alonix S;Fedipin;Coracten;Vasdalat;Fenamon SR;Adalat 20;Nifedirex LP;Nifelat;Ecodipin;Fenamon;Pidilat;Adalat CR;Nifedin;Nifedine;Hadipine;Cordalat;Myogard;Adalat LP;Nifecard;Adalat 5;Calcilat;Nifidine;Adalat GITS;Tibricol;Nificard;Osmo-Adalat;Chronadalate LP;Sepamit;Nyefax;Nifebene;Vasofed;Tensopin;Alpha-Nifedipine Retard;Cordipin;Corotrend;Ecodipin E;Nifelat Q;Adalat FT;Adapine;Citilat;Alonix;Cardifen;Dilcor;Normadil;Adalat PA;Dipinkor;Nifdemin;Adalat Oros;Nicardia;Apo-Nifed;Fedcor;Adalate;101539-70-2;101554-38-5;11104-22-6

    CAS No.:

    21829-25-4

    Molecular Formula:

    C17H18N2O6

    InChIKeys:

    InChIKey=HYIMSNHJOBLJNT-UHFFFAOYSA-N

    Molecular Weight:

    346.34

    Exact Mass:

    346.33

    EC Number:

    244-598-3

    UNII:

    I9ZF7L6G2L

    NSC Number:

    757242

    DSSTox ID:

    DTXSID2025715

    NCI Thesaurus Code:

    C29290

    Color/Form:

    Yellow crystals

    ATC Code:

    C08CA05|C - Cardiovascular system

    HScode:

    29333990

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    110

    XLogP3:

    2

    Appearance:

    yellow powder

    Density:

    1.2109 (rough estimate)

    Melting Point:

    172-174 °C

    Boiling Point:

    475.3ºC at 760 mmHg

    Flash Point:

    241.2ºC

    Refractive Index:

    1.584

    Water Solubility:

    H2O: <0.1 g/100 mL at 19.5 ºC;DMSO: soluble

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    2.6X10-8 mm Hg at 25 deg C

    Toxicity:

    Oral-rat LD50: 1022 mg/kg; Oral-Mouse LD50: 310 mg/kg

    Flammability characteristics:

    Combustion produces toxic nitrogen oxide fumes; medicinal side effects: low blood pressure, cardiomyopathy, local blood flow disorders, hyperglycemia, psychosis

    Henrys Law Constant:

    Henry's Law constant = 7.3X10-14 atm-cu m/mol at 25 °C (est)

    Collision Cross Section:

    169.4 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Very light sensitive in solution|Hydroxyl radical reaction rate constant = 1.1X10-10 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Aqueous solutions are very sensitive to light. (NTP, 1992). Insoluble in water.

    Reactive Group:

    Amines, Phosphines, and Pyridines

    Reactivity Profile:

    NIFEDIPINE is sensitive to light.

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Nifedipine liquid-filled capsules should be protected from light and moisture and stored in tight, light-resistant containers at a temperature of 15-25 deg C, and extended-release tablets of the drug should be protected from light and moisture and stored in tight, light-resistant containers at a temperature less than 30 deg C.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,API,Vitamins,Food Additive

    Location:

    No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2019

    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    Egypt

    Bulk API Nifedipine Powder Best Price

    1 KG Sep 17, 2023
    Germany

    Nifedipine

    160 KG Dec 31, 2025
    Egypt

    Nifidipine

    1 KG May 12, 2024
    Post an enquiry for this product
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