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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Avanafil for Sale > Factory supply high purity Avanafil CAS 330784-47-9
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Factory supply high purity Avanafil CAS 330784-47-9

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CAS No.:

330784-47-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai/shenzhen

Brand:

DAZE

Packaging:

25kg/drum

Price valid (until):

2024-08-07

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutial intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


       Product Detail  



    Shop Factory supply high purity Avanafil CAS 330784-47-9-Detailed Image 1

    Avanafil was originally discovered at Tanabe Seiyaku (now Mitsubishi Tanabe). JW Pharmaceutical (previously Choongwae Pharma) and VIVUS have since developed and launched avanafil, which is an oral PDE5 inhibitor for the treatment of erectile dysfunction (ED). Although many marketed PDE5 inhibitors are available for the treatment of ED, many patients are still unable to achieve the desired results and experience undesired side-effects with these existing medications. As such, second-generation PDE5 inhibitors with enhanced PDE5 selectivity, shorter systemic half-lives, and improved tolerability are desired. Developed to meet these criteria, Avanafil exhibited good oral bioavailability and PDE5 selectivity in both preclinical studies and clinical trials. Avanafil had a short onset of action (35 min) and short half-life (1.5 h).


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    Basic Info
    Product Name:

    Avanafil

    Other Name:

    5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-;4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[N-(2-pyrimidinylmethyl)carbamoyl]pyrimidine;TA 1790;Avanafil;(S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;Spedra;330785-17-6;647841-09-6

    CAS No.:

    330784-47-9

    Molecular Formula:

    C23H26ClN7O3

    InChIKeys:

    InChIKey=WEAJZXNPAWBCOA-INIZCTEOSA-N

    Molecular Weight:

    483.95

    Exact Mass:

    483.95

    UNII:

    DR5S136IVO

    DSSTox ID:

    DTXSID50186727

    NCI Thesaurus Code:

    C74354

    ATC Code:

    G04BE10|G - Genito urinary system and sex hormones

    HScode:

    2933990090

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    125

    XLogP3:

    2.6

    Appearance:

    White solid

    Density:

    1.4±0.1 g/cm3

    Melting Point:

    150-152°C

    Refractive Index:

    1.651

    Storage Conditions:

    Refrigerator

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutial intermediate

    Location:

    No.26, dongqing road, gaoxin district, zhengzhou, P.R.China

    Payment Terms:

    TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2023

  • Inquiry History
    19 Inquiries
    Country Product Purchase Quantity Date Posted
    Australia

    Avanafil 99.90% solid 330784-47-9 HSD

    1 KG Aug 29, 2023
    India

    Avanafil Best price High quality transportation safety CAS 330784-47-9

    1 KG Oct 8, 2023
    Ecuador

    Top Quality API Raw Avanafil Powder /99% pure Avanafil/ raw powder Avanafil 330784-47-9

    200 G Sep 1, 2023
    South Africa

    Top Quality API Raw Avanafil Powder /99% pure Avanafil/ raw powder Avanafil 330784-47-9

    5 KG Jun 26, 2023
    United States

    Wholesale Avanafil

    50 KG Sep 13, 2023
    United States

    Avanafil 99.9% powder factory price safety customs delivery likes

    100 G Aug 17, 2023
    United States

    avanafil

    10 G Apr 11, 2026
    Jordan

    Avanafil powder

    1 KG Jun 18, 2025
    United States

    Avanafil Usp Powder 99% white Crystaline Powder

    10 G Feb 19, 2025
    United States

    Avanafil Usp Powder 99% white Crystaline Powder

    1 KG Feb 17, 2025
    France

    Avanafil

    1 KG Aug 5, 2024
    India

    Avanafil

    20 G Oct 17, 2023
    United States

    avanafil

    200 G Aug 18, 2023
    Pakistan

    avanafil

    14 MT May 19, 2026
    United States

    Avanafil

    1 MT Sep 20, 2025
    India

    Avanafil

    25 KG Aug 15, 2025
    Pakistan

    Avanafil

    1 KG Sep 16, 2024
    India

    Avanafil 99.9% powder factory price safety customs delivery likes

    20 G Oct 17, 2023
    Malaysia

    Avanafil CAS No:330784-47-9 Dapoxetine Hydrochloride (CAS Number: 129938-20-1)

    100 KG Apr 26, 2026
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