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High Quality USP Anti-cancer Pharmaceutical Raw Powder Bleomycin sulfate CAS 9041-93-4

Name: High Quality USP Anti-cancer Pharmaceutical Raw Powder Bleomycin sulfate CAS 9041-93-4
Brand: HyperChem
SKU: pr2502281084
Price: 500 USD
Availability: InStock

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CAS No.:

9041-93-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1g/Bag, 10g/Bag

Sample Available:

Yes

Price valid (until):

2025-03-28

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information

Description

Name	Bleomycin sulfate
CAS number	9041-93-4
EINECS number	232-925-2
Related CAS#	9041-93-4 (sulfate); 11056-06-7 (free base)
Synonym	BLEO; BLM; BLEO cell; BLEO-cell; BLEOcell; Bleolem; Bleomycin sulfate; Blenoxane; Blanoxan; (3-(2'-((3S,6R,7S,8S,11S)-1-(6-amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((R)-(((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,5'-bithiazole]-4-carboxamido)propyl)dimethylsulfonium hydrogensulfate
Description	Bleomycin sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.
Structure
Molecular Formula	C110H168N34O46S7
Molecular Weight	2927.17 g/mol
Appearance	Solid powder
Quality Standard	USP Standard
Assay	≥98%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Store in cool place. Keep container tightly closed in a dry and well ventilated place.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Bleomycin sulfate More Info

Bleomycin sulfate is a chemotherapeutic agent used primarily in the treatment of various types of cancer, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and certain types of tumors. It belongs to a class of drugs known as antineoplastic antibiotics.

Mechanism of Action

Bleomycin works by binding to DNA, causing strand breaks and inhibiting DNA synthesis and cell division. It generates free radicals that cleave DNA, leading to cell death. Bleomycin is most effective against rapidly dividing cells, such as cancer cells.

Applications

Bleomycin sulfate is used for:
Hodgkin's Lymphoma: It is part of combination chemotherapy regimens.
Non-Hodgkin's Lymphoma: Used in certain types of non-Hodgkin's lymphoma.
Testicular Cancer: Part of the treatment for testicular cancer, particularly in combination with other drugs.
Squamous Cell Carcinomas: Effective against squamous cell carcinomas of the head and neck, cervix, and skin.
Pleural Effusions: Used to treat malignant pleural effusions by instillation into the pleural space.

Safety and Side Effects

Bleomycin can cause several side effects:
Common Side Effects:
Fatigue
Nausea and vomiting
Loss of appetite
Hair loss
Skin rash or itching
Less Common but Serious Side Effects:
Pulmonary toxicity (lung damage), which can be severe and potentially fatal
Fibrosis (scarring) in the lungs
Allergic reactions (rare)
Raynaud's phenomenon (cold-induced vasospasm)
Serious side effects, such as pulmonary toxicity, require immediate medical attention.

Routes of Administration

Bleomycin sulfate is administered intravenously, intramuscularly, or subcutaneously. For pleural effusions, it is instilled into the pleural space.

Pharmacokinetics

Absorption: Bleomycin is rapidly absorbed after intramuscular or subcutaneous injection.
Distribution: It has a high volume of distribution, indicating extensive distribution into tissues.
Metabolism: Bleomycin is metabolized by bleomycin hydrolase in the body.
Elimination: The half-life of bleomycin is approximately 2 hours. It is primarily excreted via urine.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

ECHEMI Editorial Reference

Bleomycin sulfate is a DNA synthesis inhibitor with potent antitumor activity.
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.

Certificates

Basic Info

Product Name:

Bleomycin sulfate

Other Name:

Bleomycin,sulfate (salt);Bleomycin sulfate;Blenoxane;Blexane;134171-41-8

CAS No.:

9041-93-4

Molecular Formula:

H2O4S.xUnspecified

InChIKeys:

WUIABRMSWOKTOF-OCBSMOPSSA-N

Molecular Weight:

2927.17

Exact Mass:

1511.478536

EC Number:

232-925-2

DSSTox ID:

DTXSID2047800

HScode:

2941906000

Categories:

Antineoplastic Agents

Characteristics

PSA:

770

Appearance:

white powder

Melting Point:

200-204°C (dec.)

Water Solubility:

soluble in water or DMSO

Storage Conditions:

2-8°C

Toxicity:

Peritoneal-rat LD50: 240 mg/kg; peritoneal-mouse LD50: 210 mg/kg

Flammability characteristics:

Thermal decomposition to emit toxic sulfur oxide fumes

See More Bleomycin sulfate Properties 

Hazard Identification

Classification of the substance or mixture

Germ cell mutagenicity, Category 1B

Carcinogenicity, Category 2

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H340 May cause genetic defects H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Bleomycin sulfate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.
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High Quality USP Anti-cancer Pharmaceutical Raw Powder Bleomycin sulfate CAS 9041-93-4

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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