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Home > Active Pharmaceutical Ingredients > Veterinary Raw Materials > Doramectin for Sale > High Quality Antiparasitic Veterinary Raw Powder Doramectin 117704-25-3 with best price
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High Quality Antiparasitic Veterinary Raw Powder Doramectin 117704-25-3 with best price

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Unit Price: Get Latest Price
CAS No.:

117704-25-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2025-04-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Doramectin

    CAS number

    117704-25-3

    EINECS number

    601-490-4

    Synonym

    Doramectin; Dectomax; Doramectina; Doramectine; Doramectinum; UK-67994; UK 67994; UK67994; NSC-760342; NSC 760342; NSC760342; (1'R,2S,4'S,5S,6R,8'R,10'E,12'R,13'S,14'E,20'R,21'R,24'S)-6-Cyclohexyl-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-5,6-dihydro-3',7',19'-trioxaspiro[pyran-2,6'-tetracyclo[15.6.1.14,8.020,24]pentacosane]-10',14',16',22'-tetraen-2'-one

    Description

    Doramectin is a macrocyclic lactone antiparasitic that targets glutamate-gated chloride channels (GluCl) in nematodes and arthropods, causing paralysis and death of the parasite. It has a broad spectrum of activity against gastrointestinal worms, lungworms, and ectoparasites in livestock, with nanomolar IC₅₀ values against key parasitic species. As a derivative of avermectin, it exhibits prolonged efficacy due to its high lipophilicity and extended half-life, making it effective for sustained parasite control.

    Structure

    Shop High Quality Antiparasitic Veterinary Raw Powder Doramectin 117704-25-3 with best price-Detailed Image 1

    Molecular Formula

    C50H74O14

    Molecular Weight

    899.11 g/mol

    Appearance

    Solid powder

    Quality Standard

    USP/EP Standard

    Assay

    ≥98%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Store in cool place. Keep container tightly closed in a dry and well ventilated place.

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Doramectin More Info

    Doramectin is a macrocyclic lactone antiparasitic medication used primarily to treat internal and external parasites in livestock, such as cattle, sheep, and pigs. It is effective against a wide range of parasites, including nematodes, arthropods, and mites.

    Mechanism of Action

    Doramectin acts by binding to GABA-gated chloride channels in parasites, causing an influx of chloride ions into the parasite's nervous system. This leads to paralysis and death of the parasites.

    Applications

    Doramectin is used for:
    Parasite Control in Livestock: It is effective against various internal parasites (e.g., gastrointestinal worms) and external parasites (e.g., ticks, lice).
    Heartworm Prevention: Doramectin may be used off-label for heartworm prevention in certain animals.
    Dermatological Conditions: It may be used to treat skin conditions caused by ectoparasites.

    Safety and Side Effects

    Doramectin is generally safe when used as directed, but some side effects may occur:
    Conmon Side Effects:
    Gastrointestinal disturbances (diarrhea, vomiting)
    Injection site reactions (swelling, pain)
    Less Common Side Effects:
    Allergic reactions (rare)
    Neurological signs (e.g., tremors, seizures) in sensitive animals
    Serious side effects require immediate veterinary attention.

    Routes of Administration

    Doramectin is administered subcutaneously or orally.

    Pharmacokinetics

    Absorption: Doramectin is well absorbed after subcutaneous administration, with peak plasma concentrations reached within a few days.
    Distribution: It has a high volume of distribution, indicating distribution into tissues.
    Metabolism: Doramectin is metabolized by the liver.
    Elimination: The half-life of doramectin is approximately 4-6 days. It is primarily excreted via feces.



    Package Image

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    FAQ

    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.


    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...


    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.


    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 


    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.


    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.



    Company Profile

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.


    Among them, our key client industrial sectors around the global are:

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply


    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.




    Certificates
    • High Quality Antiparasitic Veterinary Raw Powder Doramectin 117704-25-3 with best price Certificates 1

    Basic Info
    Product Name:

    Doramectin

    Other Name:

    Avermectin A1a,25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-;Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran],avermectin A1a deriv.;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a;Doramectin;UK 67994;25-Cyclohexylavermectin B1;Dectomax;L 701023;Doramectin A1a;Treo ACE;Treo Ace Injetavel;157544-18-8

    CAS No.:

    117704-25-3

    Molecular Formula:

    C50H74O14

    InChIKeys:

    InChIKey=QLFZZSKTJWDQOS-YDBLARSUSA-N

    Molecular Weight:

    899.11

    Exact Mass:

    899.11

    EC Number:

    1308068-626-2

    HScode:

    29419090

    Characteristics
    PSA:

    170

    XLogP3:

    5.91160

    Appearance:

    white

    Density:

    1.25±0.1 g/cm3(Predicted)

    Melting Point:

    116-119 °C

    Boiling Point:

    967.4±65.0 °C(Predicted)

    Flash Point:

    274.4±27.8 °C

    Refractive Index:

    1.580

    Water Solubility:

    methanol: soluble

    Storage Conditions:

    0-6°C

    Vapor Pressure:

    0mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Reproductive toxicity, Category 2

    Reproductive toxicity, Additional category for effects on or via lactation

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H361 Suspected of damaging fertility or the unborn child

    H362 May cause harm to breast-fed children

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P263 Avoid contact during pregnancy and while nursing.

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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    0.25 KG Jul 30, 2024
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    5 KG Mar 7, 2024
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