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Bulk NRCL Food Grade - Reliable Cellular Support Ingredient

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CAS No.:

23111-00-4

Grade:

Cosmetics Grade

Content:

99%

Port:

beijing

Brand:

SINOV

Packaging:

1Kg/Cardboard Drum

Price valid (until):

2026-01-04

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Description

NRCL (Nicotinamide Ribosyl Chloride) is a derivative of vitamin B3 and a key precursor of NAD+ (Nicotinamide Adenine Dinucleotide). It is formed by the chlorination of nicotinamide riboside (NR), with a more stable molecular structure than NR. The human body can absorb NRCL and convert it into NR, which then participates in NAD+ synthesis. Due to its chlorinated form, it has better stability in formulations compared to unmodified NR, making it suitable for a variety of product forms without easy degradation.

Application

（1）NRCL is widely used as an active ingredient in dietary supplements, nutraceutical formulations, and research reagents. It also finds application in the development of functional foods aimed at supporting cellular health.

（2）NRCL is a high-purity synthetic compound with excellent biocompatibility. It shows no obvious irritation in normal usage and is suitable for long-term inclusion in dietary supplements. It can enhance the effectiveness of other NAD+-related ingredients in formulations and is commonly used in products targeting energy metabolism and cellular vitality. Most commercial NRCL products are produced through precise chemical synthesis, ensuring high purity, while lower-purity forms are mainly used in preliminary experimental studies.

（3）In laboratory research, NRCL is often used as a standard reagent to study NAD+ synthesis pathways, investigate the mechanism of action of vitamin B3 derivatives, and explore their effects on cellular functions, serving as an important tool in metabolic and biochemical research.

Main Efficacy

NRCL is a vitamin B3 derivative obtained through chemical modification of nicotinamide riboside, with unique properties that make it an effective NAD+ precursor. It has good solubility in water and organic solvents, ensuring efficient absorption and utilization in the body.

（1）NRCL: Supports the maintenance of NAD+ levels in cells, effectively promotes the activity of enzymes involved in energy metabolism, and helps balance the metabolic state of various tissues.

（2）NRCL has a strong affinity for intestinal epithelial cells, facilitating rapid absorption in the digestive tract. It can then be transported to various tissues through the bloodstream to participate in NAD+ synthesis, supporting normal cellular physiological activities.

（3）NRCL can enhance the function of NAD+-dependent enzymes, such as poly(ADP-ribose) polymerases (PARPs), which are involved in DNA repair processes, thereby contributing to the maintenance of genome stability and cellular integrity.

（4）NRCL also supports the regulation of redox balance in cells, reduces the impact of oxidative stress on cellular components, and assists in the recovery of cellular functions after mild damage, contributing to overall cellular health.

4. Applications

Biomedical:
- Drug Delivery: Acts as a carrier to enhance drug stability and targeting.
- Tissue Engineering: Used in hydrogels and scaffolds to promote cell proliferation and tissue repair.
- Wound Healing: Exhibits antimicrobial, hemostatic, and pro-healing effects.
Cosmetics: Functions as a moisturizer, film former, and thickener, improving product texture and efficacy.
Agriculture: Serves as a plant growth regulator and soil conditioner to enhance crop resilience.
Environmental Protection: Applied in heavy metal ion adsorption and water treatment.

5. Biological Activities

Antimicrobial: Inhibits various bacteria and fungi by disrupting cell membranes and interfering with metabolism.
Antioxidant: Scavenges free radicals, protecting cells from oxidative damage.
Immunomodulatory: Enhances immune function and promotes wound healing and tissue regeneration.

6. Safety
CMCS is non-toxic, non-irritating, and biocompatible, widely used in pharmaceuticals and food.

7. Advantages and Challenges

Advantages: High water solubility, biocompatibility, functional diversity, and ease of chemical modification.
Challenges: High production costs and sensitivity of properties to substitution degree and molecular weight, requiring process optimization.

Conclusion
Carboxymethyl chitosan, as a crucial chitosan derivative, has expanded its applications through chemical modification. Leveraging its excellent water solubility, biocompatibility, and versatility, CMCS holds promising prospects in biomedical, cosmetic, agricultural, and environmental fields. Future advancements in synthesis and application research will likely unlock its potential in even more domains.

Shop Cosmetic Raw Materials Hyaluronic Acid Powder-Detailed Image 1

Items	Specifications
Origin	China
Purity	5%-99%
Appearance	Powder
Color	White
Package	Drum, Plastic Container, Vacuum Packed
Shelf life	2 years
Storage	Cool Dry Place

Certificates

Basic Info

Product Name:

Nicotinamide riboside chloride

Other Name:

Nicotinamide riboside chloride;Nicotinamide Riboside.Cl;Nicotimide riboside chloride;Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1);3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride;3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride;3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride;Nicotinamide Riboside Chloride（NRC）

CAS No.:

23111-00-4

Molecular Formula:

C11H15ClN2O5

InChIKeys:

YABIFCKURFRPPO-TUHHAUDNNA-N

Molecular Weight:

290.7

EC Number:

200-184-4

Color/Form:

White

HScode:

2938909090

Categories:

Polypeptide

Characteristics

Water Solubility:

10mg/mL, clear, colorless

Critical Temperature & Pressure:

under inert gas (nitrogen or Argon) at 2-8°C

See More Nicotinamide riboside chloride Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Nicotinamide riboside chloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Nicotinamide riboside chloride 98% NR 23111-00-4	5 MT	Jun 22, 2024
Pakistan	Wholesale Nicotinamide Riboside Chloride Powder 99% Powder Evergreen EGC-Nicotinamide Riboside Chloride CAS 23111-00-4	50 KG	Oct 17, 2023
United States	nicotinamide riboside chloride	1 KG	Feb 27, 2024
Philippines	NRcl	1 KG	Mar 1, 2026
United States	β-Nicotinamide Riboside Chloride	1 KG	Nov 22, 2024

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