(R)-4-methyl-1,3,2-dioxathiolane 2,2-dioxide RC00225

Manufacturer: Hangzhou Royalchem Co.,LTD.

Website:   www.cnroyalchem.com

【 Providing a complete set of intermediates and impurities for Orforglipron 】

【 Providing a complete set of intermediates and impurities for Orforglipron 】

【 Providing a complete set of intermediates and impurities for Orforglipron 】

Here is a detailed product description for  1006381-03-8 (R)-4-methyl-1,3,2-dioxathiolane 2,2-dioxide :

1. Chemical Identification  *  CAS Registry Number:  1006381-03-8 *  Systematic Name (IUPAC):   (4R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide  *  Common Names:  * (R)-4-Methyl-1,3,2-dioxathiolane-2,2-dioxide * (R)-4-Methyl-2-sulfato-1,3,2-dioxathiolane (emphasizes the sulfate ester) *  (R)-Propylene Sulfate  (Common trivial name, specifies stereochemistry) * (R)-1,2-Propylene glycol cyclic sulfate *  Molecular Formula:  C₃H₆O₄S *  Molecular Weight:  138.14 g/mol

2. Structural Features  *  Core Structure:  A 5-membered cyclic sulfate ester ring (1,3,2-dioxathiolane 2,2-dioxide). *  Chirality:  Contains one stereogenic center at the carbon atom adjacent to the ring oxygen (position 4). The  (R)  prefix denotes the specific absolute configuration at this chiral center. *  Functional Group:  A highly reactive cyclic sulfate group (-SO₂-O-CHR-CHR-O-). This group is electrophilic and readily undergoes ring-opening reactions with various nucleophiles.

3. Stereochemistry  * The  (R)  enantiomer is specified. This is crucial as its reactivity and the stereochemistry of products formed upon ring-opening differ significantly from the  (S) -enantiomer. Enantiomeric purity is a critical quality parameter, often specified by the supplier (e.g., >98% ee, >99% ee).