 Home > Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines > Thiamine pyrophosphate for Sale > EAST CHEM Thiamine Pyrophosphate

EAST CHEM Thiamine Pyrophosphate buy - large image1

EAST CHEM Thiamine Pyrophosphate

12 Inquiries

Unit Price: Get Latest Price 

CAS No.:

154-87-0

Content:

99%

Port:

QINGDAO

Packaging:

25KG/DRUM

Price valid (until):

2025-10-01

Contact Supplier

 Chat Now

QINGDAO EAST CHEMSOURCES TRADE CO.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

Product Identification

Item	Details
Chemical Name	Thiamine pyrophosphate; Thiamine diphosphate; TPP; Cocarboxylase
Synonyms	3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(2-phosphonooxyethyl)thiazolium diphosphate
CAS Number	154-87-0
Molecular Formula	C₁₂H₁₉N₄O₇P₂S
Molecular Weight	420.31 g/mol
Product Grade	Pharmaceutical Grade; Food Grade; Cosmetic Grade

2. Physical and Chemical Properties

Property	Specification
Appearance	White to off-white crystalline powder; odorless or slight characteristic odor

pH Value	2.5 – 3.5 (1% aqueous solution)
Melting Point	Decomposes at ≈ 240 – 250°C (no sharp melting point)
Optical Rotation	[α]ᵈ²⁰: +10.5° to +13.5° (10% aqueous solution)
Stability	Stable in acidic solutions; unstable in alkaline conditions, heat, and light

3. Quality Specifications (Typical Values)

Parameter	Pharmaceutical Grade	Food Grade
Assay (Dry Basis)	≥ 98.0%	≥ 97.0%
Loss on Drying	≤ 5.0%	≤ 5.0%
Residue on Ignition	≤ 0.1%	≤ 0.2%
Heavy Metals (as Pb)	≤ 10 ppm	≤ 20 ppm
Arsenic (As)	≤ 2 ppm	≤ 3 ppm
Chloride (Cl⁻)	≤ 0.05%	≤ 0.1%
Sulfate (SO₄²⁻)	≤ 0.05%	≤ 0.1%
Free Thiamine	≤ 1.0%	≤ 1.5%

4. Applications

TPP is the biologically active form of vitamin B₁ (thiamine) and is widely used in the following fields:

4.1 Pharmaceutical Industry

Treatment of thiamine deficiency-related diseases (e.g., beriberi, Wernicke-Korsakoff syndrome).
Adjuvant therapy for neuritis, neuralgia, and post-operative fatigue.
Injection formulations for intravenous/intramuscular administration.

4.2 Food & Feed Industry

Food fortification: Added to cereals, infant formulas, energy drinks, and dairy products to supplement vitamin B₁ activity.
Feed additive: Used in poultry, livestock, and aquaculture feeds to improve growth performance and prevent thiamine deficiency.

4.3 Cosmetic Industry

Added to anti-aging and hair-care products to support skin barrier function and hair follicle health (via metabolic regulation).

4.4 Biochemical Research

Used as a coenzyme in enzymatic reactions (e.g., pyruvate dehydrogenase, α-ketoglutarate dehydrogenase) for in vitro experiments.

5. Storage and Handling

5.1 Storage Conditions

Store in a cool, dry, and dark place at temperatures between 2 – 8°C (preferred) or ≤ 25°C.
Keep in tightly sealed original containers to protect from moisture, light, and oxygen.
Avoid contact with alkaline substances and strong oxidizing agents.

5.2 Shelf Life

24 months from the date of manufacture when stored under recommended conditions (unopened).
Once opened, use within 3 months and reseal immediately.

5.3 Handling Precautions

Use appropriate personal protective equipment (PPE): gloves, dust mask, and safety goggles when handling bulk powder.
Avoid inhalation of dust or contact with eyes/mucous membranes. In case of contact, rinse thoroughly with water.
If ingested in large quantities, seek medical attention immediately.

Basic Info

Product Name:

Thiamine pyrophosphate

Other Name:

Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-,chloride (1:1);Thiamine,trihydrogen pyrophosphate (ester);Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)-,chloride,P,P′-dioxide;Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-,chloride;Berolase;Biosyth;Bioxilasi;Bivitasi;Cocarbina;Cocarboxylase;TDP;Thiamine diphosphate;Thiamine diphosphate ester chloride;Thiamine diphosphoric acid ester chloride;Thiamine pyrophosphate;Thiamine pyrophosphate chloride;Thiamine pyrophosphoric acid ester chloride;Thiamine pyrophosphoric ester;Diphosphothiamine;Thiamine pyrophosphate hydrochloride;Thiamine-PP;Pyruvodehydrase;Farmaneurina;B-Neurox;Cocarboxil;Co-B1;Pyrolase;Coenbione;Thiamin pyrophosphate;Diphosphothiamin;TDP (thiamin ester);Metabolase;Nutrase;Coxylase;TPP;TPP (coenzyme);Vitamin B1 pyrophosphate chloride;55056-45-6;74992-00-0;902463-63-2

CAS No.:

154-87-0

Molecular Formula:

C12H19N4O7P2S.Cl

InChIKeys:

InChIKey=YXVCLPJQTZXJLH-UHFFFAOYSA-N

Molecular Weight:

460.77

Exact Mass:

460.013824

EC Number:

205-230-7

UNII:

XMK8K8EVIU

DSSTox ID:

DTXSID6046262

HScode:

29362200

Categories:

Vitamins and Minerals Medicines

Characteristics

PSA:

197

Melting Point:

238-240 °C (decomp)

Water Solubility:

It is soluble in water.

Storage Conditions:

2-8°C

Toxicity:

LD50 intramuscular in mouse: > 1gm/kg

Collision Cross Section:

182 Å² [M]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|181.8 Å² [M]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|186.8 Å² [M+Na-H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|178.2 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

See More Thiamine pyrophosphate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Thiamine pyrophosphate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

Location:
Room 501, Unit 6, No. 40, hushan road,Licang,Qingdao

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2017

QINGDAO EASTCHEMSORCES TRADE LIMITED is a leading Manufactory supplier of Sorbitol, Citric acid, Sodium hypochlorite based in Qingdao, Shandong, China. With a commitment to quality and customer satisfaction, QINGDAO EASTCHEMSORCES TRADE LIMITED has become a trusted name in the industry. Our product line includes a range of high-quality Sorbitol, Citric acid, Sodium hypochlorite, which are available at competitive prices. QINGDAO EASTCHEMSORCES TRADE LIMITED has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History