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Azathioprine

HALAL KOSHER ISO FDA COA

Unit Price: Get Latest Price
CAS No.:

446-86-6

Grade:

Medical Grade

Content:

99%

Brand:

Belibeve

Packaging:

25kg/Drum

Price valid (until):

2025-11-17

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Azathioprine is one of the derivatives of the chemical compound 6-mercaptopurine, which belongs to immunosuppressive drugs. It is a derivative of mercaptopurine, which functions by breaking down into mercaptopurine in the body. Mainly used to suppress immune rejection during allogeneic transplantation, often combined with corticosteroids. It is also widely used for autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, autoimmune hemolytic anemia, thrombocytopenic purpura, active chronic hepatitis, ulcerative colitis, myasthenia gravis, scleroderma, etc. Strict blood tests should be conducted during medication; Patients with liver dysfunction are prohibited from using it. When used in combination with corticosteroids, the oral cavity is prone to viral infections such as herpes zoster, herpes simplex, and chickenpox. Pregnant women are prohibited from using it.


      Company Detail  


    Shandong Believe Chemical Pte. Ltd, is a high-tech enterprise specializing in the R&D, production, and sales of pharmaceutical intermediates, fine chemicals, electronic material intermediates, and dye intermediates. Based in one of China’s key chemical industry hubs, the company leverages strong technical expertise, stringent quality control systems, and comprehensive customer service to become a trusted supplier for global partners in related sectors.

    Core Business Areas
    Pharmaceutical Intermediates

    Supplies high-purity, advanced intermediates such as fluorobenzene, boronic acid, and heterocyclic compounds, tailored for innovative and generic drug synthesis.

    Fine Chemicals

    Provides customized fine chemicals for catalysts, surfactants, and specialty additives to meet precise industrial process requirements.

    Electronic Material Intermediates

    Offers critical high-purity intermediates (e.g., fluorine/sulfur-containing compounds) for semiconductors, LCDs, photoresists, and new energy battery materials.

    Dye Intermediates

    Manufactures key intermediates for high-performance, eco-friendly dyes and pigments, ensuring vibrant color and consistent quality.

    Our Strengths
    R&D-Driven Innovation: A dedicated team and advanced laboratory enable continuous process optimization and custom synthesis capabilities.

    Stringent Quality Assurance: Full-process quality control from raw materials to finished products ensures high purity, consistency, and reliability.

    Integrated Production Capacity: Modern facilities support seamless scaling from pilot to large-scale production, guaranteeing stable supply.

    Customer-Centric Approach: Competitive pricing, flexible supply chain solutions, and professional technical support foster long-term partnerships.

    Vision & Values
    Guided by the principles of Innovation, Quality, and Responsibility, Shandong Billy Fluorine Chemical aims to deliver superior chemical products and services worldwide, positioning itself as a leader in the fine chemical industry.

    Contact Us:
    For inquiries and collaboration, we welcome you to reach out. Let’s create success together.

    Certificates

    Basic Info
    Product Name:

    Azathioprine

    Other Name:

    9H-Purine,6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-;Purine,6-[(1-methyl-4-nitroimidazol-5-yl)thio]-;1H-Purine,6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-;6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine;NSC 39084;Azathioprine;Azothioprine;Imuran;6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine;6-(1-Methyl-4-nitromidazol-5-ylthio)purine;Muran;BW 57-322;Imurel;Imurek;Azathioprin;Azanin;Azoran;Azamune;Azathropine;Azafor;Azasan;6165-04-4;11120-16-4;33609-91-5

    CAS No.:

    446-86-6

    Molecular Formula:

    C9H7N7O2S

    InChIKeys:

    InChIKey=LMEKQMALGUDUQG-UHFFFAOYSA-N

    Molecular Weight:

    277.27

    Exact Mass:

    277.26

    EC Number:

    207-175-4

    UNII:

    MRK240IY2L

    NSC Number:

    755900|39084

    DSSTox ID:

    DTXSID4020119

    NCI Thesaurus Code:

    C290

    Color/Form:

    Pale yellow crystals from 50% aq acetone

    ATC Code:

    L04AX01|L - Antineoplastic and immunomodulating agents

    HScode:

    2933990090

    Categories:

    Inhibitors

    Characteristics
    PSA:

    143

    XLogP3:

    0.1

    Appearance:

    Azathioprine appears as pale yellow crystals or yellowish powder. Decomposes at 243-244°C. Used for the treatment of rheumatoid arthritis. A known carcinogen.

    Density:

    1.9±0.1 g/cm3

    Melting Point:

    243.5 °C

    Boiling Point:

    555.8°C at 760 mmHg

    Flash Point:

    368.5±31.5 °C

    Refractive Index:

    1.924

    Water Solubility:

    H2O: <0.1 g/100 mL at 23 ºC;soluble in Dichloromethane and dimethyl sulfoxide.

    Storage Conditions:

    Freezer

    Vapor Pressure:

    7.98E-12mmHg at 25°C

    Toxicity:

    Oral-rat LD50: 535 mg/kg; Oral-Mouse LD50: 1389 mg/kg

    Flammability characteristics:

    It can burn and produce toxic nitrogen and sulfur oxide fumes; side effects of patients after use: changes in liver function, excessive gastrointestinal movement, nausea, vomiting, diarrhea, increased body temperature, low blood pressure, low urine output, no urine

    PKA:

    7.87(at 25 °C)

    Dissociation Constants:

    7.87 (at 25 °C)|pKa = 8.2

    Collision Cross Section:

    155.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Soly in water: 10 mg/ml /Sodium salt/

    Air and Water Reactions:

    Sensitive to oxidation in the air. Insoluble in water.

    Reactive Group:

    Amines, Phosphines, and Pyridines

    Reactivity Profile:

    AZATHIOPRINE may react exothermically with acids. Incompatible with isocyanates, peroxides, phenols, epoxides, anhydrides, and acid halides. Hydrolyzed by strongly basic solutions (NTP, 1992). May react with strong reducing agents to generate flammable gaseous hydrogen or hydrogen sulfide.

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    Germ cell mutagenicity, Category 1A

    Carcinogenicity, Category 1A

    Reproductive toxicity, Category 1A

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    H340 May cause genetic defects

    H350 May cause cancer

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Storage of the constituted soln in the original vial and in plastic syringes (Jelco) at 20-25 deg C under fluorescent light resulted in no decomp or precipitation in 16 days. At 4 deg C in the dark, a visible precipitate formed after four days. Azathioprine sodium

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    (R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

    Location:

    ROOM 574 JIUDINGFENG LARGE BUILDING NO.888 CHANGBAISHAN ROAD QINGDAO AREA CHINA (SHANDONG) PILOT FREE TRADE ZONE

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    101-200

    Year of Establishment:

    2020

    Certifications:

    ISO,SGS

  • Country Product Purchase Quantity Date Posted
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