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N,N-Diisopropylethylamine CAS:7087-68-5

Name: N,N-Diisopropylethylamine CAS:7087-68-5
Brand: Orient
SKU: pr2511261120
Price: 2 USD
Availability: InStock

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CAS No.:

7087-68-5

Grade:

Food Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25kg/bag,500kg/bag, customized

Price valid (until):

2025-12-26

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

N,N-Diisopropylethylamine Basic information

Description Stability and Reactivity Applications

Product Name:	N,N-Diisopropylethylamine
Synonyms:	3-METHYL-1-BUTINE-3-OL;N,N-DIISOPROPYLETHYLAMINE (ATOFINA EDIPA;N N-DIISOPROPYLETHYLAMINE (ATOFINA ED&;N N-DIISOPROPYLETHYLAMINE REAGENTPLUS(&;N-ETHYLDIISOPROPYLAMINE SOLUTION, ~2 M;N,N-DIISOPROPYLETHYLAMINE, BIOTECH GRADE SOLVENT, 99.5%;N-ETHYLDIISOPROPYLAMINE, 4X25 ML VIALS;N,N-Di-#niso-propylethylamine
CAS:	7087-68-5
MF:	C8H19N
MW:	129.24
EINECS:	230-392-0
Product Categories:	ACS and Reagent Grade Solvents;Combinatorial Chemistry;Synthetic Organic Chemistry;Chemistry;construction;Other Reagents;Detection of Amines for Primary Amines (for Detection of Free Amine on the Resins);Amber Glass Bottles;Essential Chemicals;Inorganic Salts;Reagent Plus;ReagentPlus;ReagentPlus Solvent Grade Products;Research Essentials;Solutions and Reagents;Solvent Bottles;Solvent by Application;Solvent Packaging Options;Solvents;bc0001;7087-68-5
Mol File:	7087-68-5.mol

N,N-Diisopropylethylamine Chemical Properties

Melting point	<-50 °C (lit.)
Boiling point	127 °C (lit.)
density	0.742 g/mL at 25 °C (lit.)
vapor pressure	31 mmHg ( 37.7 °C)
refractive index	n20/D 1.457
Fp	6 °C
storage temp.	Store below +30°C.
solubility	miscible
form	Liquid
pka	10.98±0.28(Predicted)
Specific Gravity	0.755 (20/4℃)
color	APHA: <20
PH	12.3 (H2O, 20℃)(as an emulsion)
explosive limit	0.7-6.3%(V)
Water Solubility	miscible
BRN	605301
Stability:	Volatile
InChIKey	JGFZNNIVVJXRND-UHFFFAOYSA-N
LogP	-1.8 at 22.5℃
CAS DataBase Reference	7087-68-5(CAS DataBase Reference)
NIST Chemistry Reference	(i-C3H7)2(C2H5)N(7087-68-5)
EPA Substance Registry System	2-Propanamine, N-ethyl-N-(1-methylethyl)- (7087-68-5)

Safety Information

Hazard Codes	C,F,T
Risk Statements	11-22-34-52/53-20/21/22-10-41-37/38-20/22-36/37/38-61
Safety Statements	26-36/37/39-45-61-16-27-60-23-9-53
RIDADR	UN 2734 8/PG 2
WGK Germany	2
F	9-34
Autoignition Temperature	240 °C
Hazard Note	Highly Flammable/Corrosive/Harmful
TSCA	Yes
HazardClass	3
PackingGroup	II
HS Code	29211980
Toxicity	LD50 orally in Rabbit: > 200 - 500 mg/kg

N,N-Diisopropylethylamine Usage And Synthesis

Description	N,N-Diisopropylethylamine is also known as Hunig's base and abbreviated as DIPEA or DIEA, It is a sterically hindered amine and an organic compound. The colourless liquid was named as Hung’s base after Siegfried Hunig, a German chemist. It is noteworthy that the compound is commercially available. In organic chemistry, N,N-Diisopropylethylamine is used as a base. Since the nitrogen centre is isolated by an ethyl group and the two isopropyl groups, It can bind to protons. The compound is, therefore, a base similar to 2,2,6,6-tetramethylpiperidine, but a poor nucleophile, a blend of properties that makes it valuable as an organic reagent.
Stability and Reactivity	DIPEA exhibits violent reaction as well as flammability with nitrates, oxidizing agents, and peroxides. It can also react very exothermically and possibility of spitting with halogens and strong acids. In an alkaline environment, the compound is likely to react violently. In addition, the compound can form toxic products such as n-nitrosamines when combined with nitrous acid as well as oxygen, nitrosating agents, and nitrates. Under normal conditions (temperature and pressure), DIPEA is very stable. However, it is soluble in most organic solvents.
Applications	N,N-Diisopropylethylamine is utilized as a base in the palladium(0)catalysed alkoxycarbonylation of both allyl acetates and phosphates. It is used as a neutralizer of the produced phosphoric acid. Notably, the alkyl ester cannot be produced without DIPEA. When combined with boryl triflates, N,N-Diisopropylethylamine is used in the enolate synthesis of ketones for application in directed cross-adol reactions. DIPEA is applied as a proton scavenger in organic synthesis. Since the compound is a sterically hindered amine, it lacks quaternization; therefore, making it a perfect choice of a base for use with extremely reactive alkylating agents. DIPEA is specifically useful as a base in the protection of alcohols as substituted ethers in the field of protecting group chemistry. In the synthesis of peptides, the compound is also used in the coupling of amino acids. The steric nature and basicity of DIPEA during the coupling reaction affects the degree of racemization.
Chemical Properties	Diisopropylethylamine (DIPEA) is a clear, colorless to light yellow liquid, insoluble in water and easily soluble in acetone and other organic solvents.
Uses	N,N-Diisopropylethylamine is used as a base in organic reactions. Used in the preparation of (-)Gambierol a marine polycyclic ether toxin. It is also used in the synthesis of potent inhibitors of human brain memapsin, a key effector in the progression of Alzheimer’s disease.

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Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Diisopropylethylamine

Other Name:

2-Propanamine,N-ethyl-N-(1-methylethyl)-;Triethylamine,1,1′-dimethyl-;N-Ethyl-N-(1-methylethyl)-2-propanamine;N-Ethyldiisopropylamine;Ethyldiisopropylamine;N-Ethyl-N,N-diisopropylamine;N,N-Diisopropylethylamine;Diisopropylethylamine;1,1′-Dimethyltriethylamine;Huenig's base;Hunig's base;DIEA;Hunig's reagent;Bis(1-methylethyl)ethylamine;NSC 147491;Ethyl-N,N-diisopropylamine;N,N-Bis(1-methylethyl)-N-ethylamine;N-Ethyl-N-isopropylpropan-2-amine;DIPEA;N-Ethyl-N-propan-2-ylpropan-2-amine;Ethylbis(propan-2-yl)amine;1200454-07-4

CAS No.:

7087-68-5

Molecular Formula:

C8H19N

InChIKeys:

InChIKey=JGFZNNIVVJXRND-UHFFFAOYSA-N

Molecular Weight:

129.24

Exact Mass:

129.24

BRN:

605301

EC Number:

230-392-0

UNII:

5SIQ15721L

NSC Number:

147491

DSSTox ID:

DTXSID8064561

HScode:

29211980

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

3.2

XLogP3:

2.35

Appearance:

APHA: <20 Liquid

Density:

0.8±0.1 g/cm3

Melting Point:

126-128 °C

Boiling Point:

126.5 °C

Flash Point:

6 °C

Refractive Index:

1.421

Water Solubility:

miscible

Storage Conditions:

Store in dark!

Vapor Pressure:

31 mmHg ( 37.7 °C)

Toxicity:

LD50 orally in Rabbit: > 200 - 500 mg/kg

Explosive limit:

0.7-6.3%(V)

See More Diisopropylethylamine Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 2

Acute toxicity - Category 4, Oral

Serious eye damage, Category 1

Acute toxicity - Category 3, Inhalation

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H225 Highly flammable liquid and vapour H302 Harmful if swallowed H318 Causes serious eye damage H331 Toxic if inhaled H335 May cause respiratory irritation
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P319 Get medical help if you feel unwell.
Storage	P403+P235 Store in a well-ventilated place. Keep cool. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Diisopropylethylamine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	DIPEA	67.6 TON	May 24, 2024
Egypt	N-Ethyldiisopropylamine ( EDIPA )	72 TON	May 15, 2024
India	NN DIISOPROPYLETHYLAMINE	450.00 KG	Oct 16, 2023
United States	Hunig's Base (N,N-Diisopropylethylamine)	10 MT	Jan 6, 2026
Russia	N,N-Diisopropylethylamine	1000 KG	May 7, 2024
Russia	DIPEA	1500 KG	Jun 23, 2023
South Africa	DIPEA (N,N-Diisopropylethylamine)	5 KG	Jan 12, 2026

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