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2-Chlorotoluene CAS:95-49-8

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CAS No.:

95-49-8

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2025-12-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Items Specifications
    Product name 2-Chlorotoluene
    CAS 95-49-8
    Appearance LIQUID
    Uses

    Solvent and intermediate for organic chemicals and dyes.
    2-Chlorotoluene is used for permanganate oxidation to give o-chlorobenzoic acid. It is used in the preparation of 3-chloro-4-methylcatechol and 4-chloro-3-methylcatechol.
    2-Chlorotoluene can be used as a precursor to synthesize aryl coupling products via palladium-catalyzed Negishi cross-coupling. It can also be used in the Buchwald-Hartwig amination to synthesize arylamines.

    Solvent; synthesis of dyes, pharmaceuticals, and synthetic rubber compounds

    Preparation The solution of cuprous chloride is cooled in an ice bath 0-5° C temperature. In this cold solution, the 2-methylbenzenediazonium is poured with constant shaking and allowing the mixture to come to room temperature. After about 10 minutes, the mixture gradually warmed with a good shaking.As the temperature rises the brown addition product begins to decompose with the evolution of nitrogen and with the formation of an oily layer of 2-chlorotoluene. When the decomposition reaction is at an end, the mixture is steam distilled, continuing the process only as long as oily droplets are present in the distillate, for the product is not appreciably soluble in water. The layer of 2-chlorotoluene is carefully separated and washed twice with an equal volume of concentrated sulfuric acid, which removes both the 2-cresol and the azo compound. Then 2-chlorotoluene is washed with water in order to remove the inorganic acid. Finally, 2-chlorotoluene is dried over calcium chloride, distilled, using an air condenser and collecting the product boiling at 153-158° C. Pure 2-chlorotoluene boils at 157° C. The yield is 25-30 g.
    Shop 2-Chlorotoluene CAS:95-49-8-Detailed Image 1
    Experiments in Organic Chemistry, L. F. Fieser, 216, 1941
    Highly Selective Oxidative Monochlorination To Synthesize Organic Intermediates: 2-Chlorotoluene, 2-Chloroaniline, 2-Chlorophenol, and 2-Chloro-4-methylphenol
    storage

    Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with o-chlorotoluene you should be trainedon its proper handling and storage. Store in tightly closedcontainers in a cool, well-ventilated area. Metal containersinvolving the transfer of this chemical should be groundedand bonded. Drums must be equipped with self-closingvalves, pressure vacuum bungs, and flame arresters. Useonly nonsparking tools and equipment, especially whenopening and closing containers of this chemical. Sources ofignition, such as smoking and open flames, are prohibitedwhere this chemical is used, handled, or stored in a mannerthat could create a potential fire or explosion hazard.

    Waste Disposal

    In accordance with 40CFR165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

    2-Chlorotoluene Chemical Properties
    Melting point  -36 °C (lit.)
    Boiling point  157-159 °C (lit.)
    density  1.083 g/mL at 25 °C (lit.)
    vapor density  4.38 (vs air)
    vapor pressure  10 mm Hg ( 43 °C)
    refractive index  n20/D 1.525(lit.)
    Fp  117 °F
    storage temp.  0-6°C
    solubility  H2O: slightly soluble0.047g/L at 20°C
    form  Liquid
    color  Clear
    explosive limit 1.0-12.6%(V)
    Water Solubility  slightly soluble
    Merck  14,2171
    BRN  1904175
    Dielectric constant 4.4500000000000002
    Exposure limits ACGIH: TWA 50 ppm
    NIOSH: TWA 50 ppm(250 mg/m3); STEL 75 ppm(375 mg/m3)
    InChIKey IBSQPLPBRSHTTG-UHFFFAOYSA-N
    LogP 3.42 at 25℃
    CAS DataBase Reference 95-49-8(CAS DataBase Reference)
    NIST Chemistry Reference Benzene, 1-chloro-2-methyl-(95-49-8)
    EPA Substance Registry System o-Chlorotoluene (95-49-8)

    Safety Information
    Hazard Codes  Xn,N,F,Xi,T
    Risk Statements  20-51/53-39/23/24/25-23/24/25-11
    Safety Statements  24/25-61-45-36/37-16-7
    RIDADR  UN 2238 3/PG 3
    OEB A
    OEL TWA: 50 ppm (250 mg/m3), STEL: 75 ppm (375 mg/m3)
    WGK Germany  2
    RTECS  XS9000000
    Autoignition Temperature 600°C
    Hazard Note  Irritant/Flammable
    TSCA  Yes
    HazardClass  3
    PackingGroup  III
    HS Code  29036990
    Hazardous Substances Data 95-49-8(Hazardous Substances Data)



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    ——  Q&A  ——

    Q1:Do you provide sample?

    A: Yes, we can provide free sample, you only need pay the shipping cost.

    Q2: What is the lead time?

    A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

    Q3: How can I buy? What is the payment method?

    A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer, 

    Q4:What if there are quality issues?

    A:We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.



    Certificates

    Basic Info
    Product Name:

    2-Chlorotoluene

    Other Name:

    Benzene,1-chloro-2-methyl-;Toluene,o-chloro-;1-Chloro-2-methylbenzene;2-Chloro-1-methylbenzene;o-Chlorotoluene;2-Chlorotoluene;1-Methyl-2-chlorobenzene;o-Tolyl chloride;2-Methylchlorobenzene;o-Methylchlorobenzene;2-Methylphenyl chloride;NSC 8766;2-Tolyl chloride;2-Methyl-1-chlorobenzene

    CAS No.:

    95-49-8

    Molecular Formula:

    C7H7Cl

    InChIKeys:

    InChIKey=IBSQPLPBRSHTTG-UHFFFAOYSA-N

    Molecular Weight:

    126.58300

    Exact Mass:

    126.58

    EC Number:

    202-424-3

    UNII:

    2G7D0YDV9H

    ICSC Number:

    1458

    NSC Number:

    8766

    UN Number:

    2238

    DSSTox ID:

    DTXSID8023977

    Color/Form:

    Colorless liquid.

    HScode:

    29036990

    Characteristics
    PSA:

    0

    XLogP3:

    2.64840

    Appearance:

    O-chlorotoluene is a colorless liquid with an aromatic odor. Denser than water and poorly soluble in water. Hence sinks in water . (USCG, 1999)

    Density:

    1.0826 g/cm3 @ Temp: 20 °C

    Melting Point:

    -35.59 °C

    Boiling Point:

    158.97 °C

    Flash Point:

    47ºC

    Refractive Index:

    1.524-1.526

    Water Solubility:

    H2O: slightly soluble

    Storage Conditions:

    0-6ºC

    Vapor Pressure:

    10 mm Hg ( 43 °C)

    Vapor Density:

    4.38 (vs air)

    Flammability characteristics:

    Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.

    Explosive limit:

    vol% in air: 12.6

    Odor:

    Aromatic odor.

    Henrys Law Constant:

    0.00 atm-m3/mole

    Experimental Properties:

    Heat of fusion = 79.99 J/g; Heat capacity = 0.355 J/g-K

    Air and Water Reactions:

    Slightly water soluble.

    Reactive Group:

    Aryl Halides

    Reactivity Profile:

    O-CHLOROTOLUENE may be incompatible with strong oxidizing and reducing agents. Also may be incompatible with amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Reacts violently with dimethyl sulfoxide (NTP, 1992).

    Heat of Combustion:

    -3747 kJ/mol @ 18.8 °C

    Ionization Potential:

    8.83 eV

    Flammable Limits:

    Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.

    Heat of Vaporization:

    329.1 J/g @ 100 °C

    Critical Temperature & Pressure:

    Critical temperature = 381.1 °C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Inhalation

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H332 Harmful if inhaled

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P273 Avoid release to the environment.

    Response

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P317 Get medical help.

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames, NO sparks and NO smoking. Above 43°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Fireproof. Separated from strong oxidants.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    OCT (Ortho Chloro Toluene)

    10.00 MT Aug 30, 2024
    India

    O-chlorotoluene

    16 MT Sep 26, 2023
    Post an enquiry for this product
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