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D-PANTHENOL 81-13-0

Name: D-PANTHENOL 81-13-0
Brand: Orient
SKU: pr2512251531
Price: 4 USD
Availability: InStock

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CAS No.:

81-13-0

Grade:

Industrail Grade

Content:

99%

Port:

shanghai

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Sample Available:

Yes

Price valid (until):

2026-01-25

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	Dexpanthenol
Synonyms:	4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(theta)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-d-(+)-butyramid;Alcopan-250;Bepanthen;Bepanthene;Bepantol;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)-
CAS:	81-13-0
MF:	C9H19NO4
MW:	205.25
EINECS:	201-327-3
Product Categories:	Inhibitors;haircare cosmetics;Pharmaceutical Intermediates;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;ILOPAN;81-13-0;bc0001
Mol File:	81-13-0.mol

Dexpanthenol Chemical Properties

Melting point	64～69℃
alpha	30.5 º (c=5, H2O on anh. sub)
Boiling point	118-120 °C (2.7 mmHg)
density	1.20 g/mL at 20 °C (lit.)
vapor pressure	0Pa at 25℃
refractive index	1.495-1.502
Fp	118-120°C/0.02m
storage temp.	2-8°C
solubility	DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
form	Viscous Liquid or Semi Solid
pka	13.03±0.20(Predicted)
color	Clear colorless to slightly yellow
PH	pH (100g/l,25℃) : 8.5～10.5
Optical Rotation	[α]20/D +30±1°, c = 5% in H2O
biological source	synthetic
Water Solubility	soluble
Sensitive	Hygroscopic
Merck	14,2947
BRN	1724947
Cosmetics Ingredients Functions	HAIR CONDITIONING SKIN CONDITIONING ANTISTATIC
InChIKey	SNPLKNRPJHDVJA-ZETCQYMHSA-N
LogP	-1.06 at 22℃
CAS DataBase Reference	81-13-0(CAS DataBase Reference)
NIST Chemistry Reference	Dexpanthenol(81-13-0)
EPA Substance Registry System	(+)-Panthenol (81-13-0)

Safety Information

Hazard Codes	Xn
Risk Statements	36/37/38-48-41-37/38-20/21/22
Safety Statements	23-24/25-45-36/37/39-26-22
WGK Germany	1
RTECS	ES4316000
F	3-10
TSCA	Yes
HS Code	29241990
Hazardous Substances Data	81-13-0(Hazardous Substances Data)
Toxicity	LD50 oral in mouse: 15gm/kg

MSDS Information

Dexpanthenol Usage And Synthesis

Description	Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine.
References	https://pubchem.ncbi.nlm.nih.gov/compound/Dexpanthenol#section=Top https://www.drugs.com/pro/dexpanthenol.html https://de.wikipedia.org/wiki/Dexpanthenol
Chemical Properties	clear colorless to slightly yellow viscous liquid
Originator	Bepanthene,Roche,France,1951
Uses	Dexpanthenol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques as well as partial least-squares multivariate calibration.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

ECHEMI Editorial Reference

D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell.
Solid
Pantothenol is a monocarboxylic acid amide that is 3,3-dimethylbutanamide substituted by hydroxy groups at positions 2 and 4 and a 3-hydroxypropyl group at the carbomyl nitrogen. It has a role as a cholinergic drug and a provitamin. It is an amino alcohol and a monocarboxylic acid amide.|Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium. Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote healing. Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties. Dexpanthenol is also available as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol) as [DB11204]. While pantothenic acid is optically active, only the dextrorotatory form (dexpanthenol) is biologically active.|Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

Certificates

Basic Info

Product Name:

(+)-Panthenol

Other Name:

Butanamide,2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,(2R)-;Butyramide,2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,D-(+)-;Butanamide,2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,(R)-;(2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide;Bepanthen;Bepanthene;Bepantol;Cozyme;Dexpanthenol;D(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide;D(+)-α,γ-Dihydroxy-N-(3-hydroxypropyl)-β,β-dimethylbutyramide;Ilopan;D-P-A Injection;Motilyn;Panadon;Panthoderm;Pantol;d-Pantothenol;d-Pantothenyl alcohol;Thenalton;Zentinic;D-Panthenol;Panthenol;Pantothenol;Pantothenyl alcohol;Propanolamine,N-pantoyl-;Panthenol,(+)-;D(+)-Pantothenyl alcohol;D(+)-Panthenol;Synapan;Provitamin B;d-Panthenol;D-Pantothenyl alcohol;Provitamin B5;d-Panthenol 50;Urupan;Alcopan 250;Pantenyl;Intrapan;(+)-Panthenol;NSC 302962;Panthenol 50W;Cornergel;Dolobene;D-Panthenol 75L;Pantogel;(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide;(2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide;1113-70-8;17307-32-3;50584-68-4

CAS No.:

81-13-0

Molecular Formula:

C9H19NO4

InChIKeys:

InChIKey=SNPLKNRPJHDVJA-ZETCQYMHSA-N

Molecular Weight:

205.251

Exact Mass:

205.25

EC Number:

201-327-3

UNII:

1O6C93RI7Z

DSSTox ID:

DTXSID3022906

NCI Thesaurus Code:

C47481

Color/Form:

Hygroscopic oil|Viscous liquid|Clear viscous, somewhat hygroscopic liquid ... Some crystallization may occur on standing

ATC Code:

D03AX03|A - Alimentary tract and metabolism|D - Dermatologicals|S - Sensory organs

HScode:

2924199090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

89.79

XLogP3:

-0.9

Appearance:

Transparent colorless to slightly yellow viscous liquid

Density:

1.2 g/cm³ @ Temp: 20 °C

Melting Point:

<25 °C

Boiling Point:

119 °C

Flash Point:

246.3ºC

Refractive Index:

1.495-1.502

Water Solubility:

In water, 1.6X10+6 mg/L at 25 deg C /miscible/ (est)

Storage Conditions:

-20ºC

Vapor Pressure:

1.5X10-8 mm Hg at 25 deg C (est)

Toxicity:

LD50 oral in mouse: 15gm/kg

Taste:

Slightly bitter taste

Henrys Law Constant:

Henry's Law constant = 2.8X10-11 cu cm/molec-sec at 25 °C (est)

Collision Cross Section:

144.7 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|141.49 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|144.1 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

The alcohol corresponding to pantothenic acid, with vitamin activity|Hydroxyl radical reaction rate constant = 2.7X10-11 cu cm/molec-sec at 25 °C (est)

See More (+)-Panthenol Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Dexpanthenol injection should be protected from freezing & excessive heat.

See More (+)-Panthenol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

21 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Dexpanthenol	100 KG	Aug 8, 2025
United Kingdom	D Panthenol	1 KG	Sep 21, 2026
Colombia	Panthenol	1.00 KG	Jun 26, 2026
Kenya	Panthenol Cosmetics	10 KG	Sep 8, 2025
India	D Panthenol	100 20' Fcl	Jun 9, 2025
India	D-Panthenol	500.00 KG	Jun 7, 2025
Poland	D-panthenol	1000 KG	Nov 21, 2024
Pakistan	Dexpanthenol	50 G	Oct 22, 2024
India	D Panthenol	50.00 G	Oct 9, 2023
Germany	d panthenol	3 MT	Aug 12, 2026
Australia	D Panthenol (Provitamin B5)	1 L	Jan 13, 2026
Turkey	DEKSPANTENOL (VİT B5)	10.00 KG	Apr 16, 2025
Russia	Dexpanthenol	250 KG	Dec 6, 2024
Russia	D-panthenol 75%	900 KG	Sep 16, 2024
India	D-panthenol 98%	500.00 KG	Jul 4, 2024
India	D-PANTHENOL 98% LIQUID	500.00 KG	Apr 3, 2024
Russia	Dexpanthenol	400 KG	Oct 16, 2024
India	d-panthenol	250.00 KG	Aug 9, 2024
India	D-panthenol	0.05 KG	Jun 12, 2024
India	d-panthenol 98%	600.00 KG	May 24, 2024

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