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Home > Food Additives > Nutrition Supplements > Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1) for Sale > EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - large image1
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - image1
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - image2
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - image3
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - image4
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - image5
EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement buy - image6

EP/USP Grade 99% S-Adenosyl-L-Methionine Disulfate Tosylate/SAMe CAS:97540-22-2 for Nutritional Supplement

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Unit Price:

$120-150/KG FOB

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CAS No.:

97540-22-2

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1g/bag, 20g/bag, 50g/bags or other quantities

Price valid (until):

2027-06-30

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description
    Name S-Adenosyl-L-methionine Disulfate Tosylate
    CAS number 97540-22-2
    Synonym SAMe ; SAM-e;C22H34N6O16S4
    Description S-Adenosyl-L-Methionine Disulfate Tosylate, commonly known as SAMe, with the CAS number 97540-22-2, is a compound of significant interest in biochemical and therapeutic fields. SAMe is the tosylate salt form of S-Adenosyl-L-Methionine (SAM), an important compound naturally occurring in the body and playing a crucial role in numerous biochemical processes.

    Description
    SAMe is a synthetic form of a compound that is naturally synthesized in the body from adenosine triphosphate (ATP) and methionine, an essential amino acid. It is often presented as a stable, crystalline salt to enhance its bioavailability and stability, making it suitable for use as a dietary supplement and in pharmaceutical applications. The disulfate tosylate form is specifically designed to improve its storage and handling characteristics.

    Mechanism of Action
    SAMe functions as a methyl group donor in numerous methylation reactions throughout the body, which are critical for various metabolic processes. These reactions affect the synthesis, activation, and breakdown of neurotransmitters, proteins, nucleic acids, and phospholipids.

    Methylation: One of the primary roles of SAMe is in the methylation process where it donates a methyl group to substrates, which can include DNA, proteins, and other molecules. This activity is crucial for regulating gene expression, protein function, and lipid metabolism.
    Transsulfuration: SAMe is also involved in the transsulfuration pathway, which leads to the production of glutathione. Glutathione is a powerful antioxidant that helps protect cells from oxidative stress, thereby playing a protective role in both detoxification and cellular defense mechanisms.
    Polyamine Synthesis: SAMe is a precursor in the formation of polyamines, which are compounds important for cellular growth and repair, emphasizing its role in maintaining cell integrity.
    The influence of SAMe in these biochemical pathways elucidates its impact on mood regulation, liver function, and joint health, which are explored in its various applications.

    Usage
    SAMe is marketed as a dietary supplement and used in various therapeutic settings due to its diverse effects on the body:
    Mood Disorders: SAMe has been extensively studied for its antidepressant properties. It influences the synthesis and modulation of key neurotransmitters such as serotonin, dopamine, and norepinephrine, thereby supporting mood regulation. Clinical studies have shown its effectiveness in alleviating symptoms of depression, with some studies suggesting comparable efficacy to traditional antidepressants but with fewer side effects.
    Liver Health: SAMe is considered beneficial in promoting liver health. It has been used in managing liver disorders due to its involvement in detoxification reactions and its ability to raise hepatic glutathione levels, thus protecting liver cells from damage.
    Joint Health: Another significant application of SAMe is in managing osteoarthritis. Research has demonstrated that it can reduce pain and improve joint function, providing an alternative to nonsteroidal anti-inflammatory drugs (NSAIDs) with a better side effect profile.
    Cognitive Support: Due to its essential role in methylation reactions affecting neurotransmitter synthesis, SAMe is being investigated for cognitive support and the potential management of cognitive decline, including conditions like Alzheimer's disease.
    Chemical Classification
    SAMe falls under the category of coenzymes and methyl donors. As a sulfonium compound, it possesses a positively charged sulfur atom with three organic substituents, highlighting its unique structural properties that enable its biological activities. The addition of the tosylate salt enhances its formulation stability, making it suitable for supplementation and pharmaceutical development.

    Additional Information
    The body’s ability to produce SAMe declines with age, which has led to increased interest in supplementation, especially among older adults. It is generally well-tolerated, although, like any supplement, there are potential interactions and contraindications, such as in individuals with bipolar disorder, where it may exacerbate manic episodes.

    Research continues to investigate the broader therapeutic benefits of SAMe, exploring its potential use in brain health, inflammatory conditions, and even certain psychiatric disorders beyond depression. This ongoing research could potentially unlock new therapeutic applications and formulations, extending its impact across various health domains.

    In conclusion, S-Adenosyl-L-Methionine Disulfate Tosylate (SAMe) is a multifaceted compound with a critical presence in numerous biochemical pathways. Its widespread usage as a supplement for supporting mental health, liver function, joint health, and possibly cognitive performance makes it an important compound in both clinical settings and among consumers seeking to enhance their health and well-being. As the scientific community continues to unveil its complex roles and benefits, SAMe remains a promising agent in the domain of health and nutrition.

     
    Molecular Formula C 22 H 34 N 6 O 16 S 4
    Molecular Weight 766.78 g/mol
    Appearance White or almost white crystalline powder
    Quality Standard USP EP
    Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
    Storage Condition Dry, dark and at 2~8 for short term (days to weeks) or -20 for long term (months to years).
    Shelf Life >2 years if stored properly
    Sample package Aluminium foil bag
    Commercial package Fiber drum
    Origin China


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    FAQ

    Q1. What is the Hyper chem payment term?
    T/T advance
    LC at sight
    DP at sight
    Trade assurance 
    Money gram 

     

    Q2. What is Hyper chem shipment policy?
    Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
    For non-ready stock, please contact the Hyper Chem sales team to negotiate.

     

    Q3. What hyper chem will provide after shipment?
    For sample orders: 
    After shipment is done, an timely email including:

    Track details (Fedex /TNT/DHL/EMS Track number)

    Package photo

    COA, MSDS, etc 

    Dispatch date & Estimated arriving time

    Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided
    in scan-copy and original, to help customers complete the customs clearance process.

     

    Q4. What is Hyper Chem shipment term?

    By Express   
    DHL  FedEx  TNT  EMS                               
    Fast:5 days around                             
    High cost, door to door service

    By Air                                         
    Suitable for more than 50kg 
    Fast :3-7 days Hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Slow:7-45 days, Low cost, port to port, professional broker needed 
    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. Does hyper chem provide a shipment return policy?
    Yes, we have.
    Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied  within 45 days of purchase for a full refund to:

     

    Q6. What is hyper chem After-sales service
    •Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
    • Customer Support: Shipment clearance support, quality issue support
    • Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

     

     

     

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

     

    Among them, our key client industrial sectors around the global are:

     

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply

     

    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

    Certificates

    Basic Info
    Product Name:

    Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1)

    Other Name:

    Adenosine,5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-,sulfate,4-methylbenzenesulfonate sulfate (1:1:1:1);Adenosine,5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-,(3S)-,sulfate (salt),4-methylbenzenesulfonate (salt) sulfate (salt) (1:1:1:1);Adenosine,5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-,sulfate (salt),4-methylbenzenesulfonate (salt) sulfate (salt) (1:1:1:1);FO 1561;S-Adenosyl-L-methionine disulfate tosylate;110899-33-7;113883-52-6;137088-54-1;89365-51-5

    CAS No.:

    97540-22-2

    Molecular Formula:

    C15H23N6O5S.C7H8O3S.H2O4S.HO4S

    InChIKeys:

    InChIKey=XDCFCHNAIMYBAZ-XQVUROGGSA-N

    Molecular Weight:

    766.8

    Exact Mass:

    766.091431

    UNII:

    R96GHU97Q3|4G5PYL0DR1|564ROC9U09

    NCI Thesaurus Code:

    C71745

    HScode:

    2934999090

    Categories:

    Nutrition Supplements

    Characteristics
    PSA:

    415

    XLogP3:

    1.20310

    Appearance:

    white powder

    Hazard Identification

    Classification of the substance or mixture

    Skin corrosion, Sub-category 1B

    Serious eye damage, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H314 Causes severe skin burns and eye damage

    H318 Causes serious eye damage

    Precautionary statement(s)
    Prevention

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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