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1-Methylimidazole 616-47-7

Name: 1-Methylimidazole 616-47-7
Brand: Orient
SKU: pr2512291211
Price: 4 USD
Availability: InStock

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CAS No.:

616-47-7

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2026-01-29

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	1-Methylimidazole
Synonyms:	N-methylimidazole (1-methylimidazole);N-methyl midazole;N-methyl glyoxaline;CAP B (1-METHYLIMIDAZOLE 12% IN ACETONIT;1-Methylimidazole, >=99%, purified by redistillation;CAP B (1-METHYLIMIDAZOLE 10% IN THF);CAP B (1-METHYLIMIDAZOLE 10% IN;CAP B (1-METHYLIMIDAZOLE 16% IN THF)
CAS:	616-47-7
MF:	C4H6N2
MW:	82.1
EINECS:	210-484-7
Product Categories:	Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;C3 to C8;Carbonate dehydratase;Histidinol dehydrogenase;A to C;and Substrates;Biochemicals and Reagents;D to K;Enzyme Inhibitors;Enzyme Inhibitors by Enzyme;Enzymes;Inhibitors;Imidazoles;Heterocyclic Compounds;Heterocycles;Metabolites & Impurities;Building Blocks;Heterocyclic Building Blocks;Carbonate dehydrataseEnzyme Inhibitors by Enzyme;Histidinol dehydrogenaseBuilding Blocks;A to;D to;Enzyme Inhibitors by Enzyme;Heterocycles, Metabolites & Impurities;616-47-7;bc0001;HL00006;R00001
Mol File:	616-47-7.mol

1-Methylimidazole Chemical Properties

Melting point	−60 °C(lit.)
Boiling point	198 °C(lit.)
density	1.03 g/mL at 25 °C(lit.)
vapor pressure	0.4 mm Hg ( 20 °C)
refractive index	n20/D 1.495(lit.)
Fp	198 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	6.95(at 25℃)
form	Liquid
color	Clear colorless to yellow
Specific Gravity	1.031
PH	9.5-10.5 (50g/l, H2O, 20℃)
PH Range	9.5 - 11.5 at 100 g/l at 20 °C
biological source	synthetic
explosive limit	2.7-15.7%(V)
Water Solubility	Miscible with water.
Sensitive	Hygroscopic
BRN	105197
Stability:	Stable, but moisture sensitive. Incompatible with acids, acid anhydrides, strong oxidizing agents, moisture, carbon dioxide, acid chlorides.
InChIKey	MCTWTZJPVLRJOU-UHFFFAOYSA-N
LogP	-0.19 at 25℃
CAS DataBase Reference	616-47-7(CAS DataBase Reference)
NIST Chemistry Reference	1H-Imidazole, 1-methyl-(616-47-7)
EPA Substance Registry System	1H-Imidazole, 1-methyl- (616-47-7)

Safety Information

Hazard Codes	C,Xn,F,T
Risk Statements	21/22-34-19-11-20/21/22-52/53-24-22-40-37-21
Safety Statements	26-36-45-1/2-36/37/39-16-33-29-61
RIDADR	UN 3267 8/PG 2
WGK Germany	1
RTECS	NI7000000
F	3-10
Autoignition Temperature	977 °F
TSCA	Yes
HazardClass	8
PackingGroup	III
HS Code	29332990
Toxicity	LD50 orally in Rabbit: 1144 mg/kg LD50 dermal Rabbit > 400 - < 640 mg/kg

MSDS Information

1-Methylimidazole Usage And Synthesis

Chemical Properties	1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. It is a colorless to yellow liquid, with an amine-like odor. It is miscible with water. N-methylimidazole is an important raw material for the synthesis of pharmaceutical intermediates, used in the preparation of losartan, nizofenone, 1-Methyl-1H-imidazole-5-carbonyl chloride hydrochloride and naphazoline hydrochloride, etc. It is also used as a specialty solvent, a base, and as a precursor to some ionic liquids.
Uses	1-Methylimidazole is an aprotic solvent. It is a derivative of imidazole used in the production of pharmaceuticals, pesticides, ion exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. It can also be used as a catalyst for the manufacture of polyurethane and a curing agent for epoxy resins. For example, when 1-methylimidazole is added to an aqueous diethylenetriamine (DETA) solution, high CO2 loading can be achieved through phase separation of the absorbent during CO2 absorption[1].
Definition	ChEBI: 1-methyl-1H-imidazole is a 1H-imidazole having a methyl substituent at the N-1 position. It is a metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.
Preparation	1-Methylimidazole is prepared mainly by two routes industrially. The main one is acid-catalysed methylation of imidazole by methanol. The second method involves the Radziszewski reaction from glyoxal, formaldehyde, and a mixture of ammonia and methylamine. (CHO)2 + CH2O + CH3NH2 + NH3 → H2C2N(NCH3)CH + 3 H2O The compound can be synthesized on a laboratory scale by methylation of imidazole at the pyridine-like nitrogen and subsequent deprotonation. Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation. H2C2N(NH)CH + CH3I → [H2C2(NH)(NCH3)CH]I [H2C2(NH)(NCH3)CH]I + NaOH → H2C2N(NCH3)CH + H2O + NaI

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

1-Methylimidazole

Other Name:

1H-Imidazole,1-methyl-;Imidazole,1-methyl-;1-Methyl-1H-imidazole;N1-Methylimidazole;N-Methylimidazole;1-Methylimidazole;N-methylimidazole;Araldite DY 070;DY 070;NSC 88064;Imicure AMI 1;Epikure 201;Kaolizer 110;69723-05-3;110069-11-9;120418-32-8;142504-34-5;674282-80-5;864745-22-2;955156-62-4;1167574-49-3;1174917-56-6;1179540-68-1;1235442-19-9;1246941-20-7;1259523-87-9;1357171-90-4;1359978-71-4;1532594-45-8;1626357-11-6;1799662-03-5;1848219-06-6;2210264-93-8

CAS No.:

616-47-7

Molecular Formula:

C4H6N2

InChIKeys:

InChIKey=MCTWTZJPVLRJOU-UHFFFAOYSA-N

Molecular Weight:

82.106

Exact Mass:

82.10

EC Number:

210-484-7

UNII:

P4617QS63Y

NSC Number:

88064

DSSTox ID:

DTXSID6052291

HScode:

2933290090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

17.8

XLogP3:

-0.1

Appearance:

Liquid

Density:

1.0370 g/cm³ @ Temp: 20.00 °C

Melting Point:

-6 °C

Boiling Point:

195.5 °C

Flash Point:

92.2±0.0 °C

Refractive Index:

1.525

Water Solubility:

Miscible with water.

Storage Conditions:

Store at RT.

Vapor Pressure:

0.4 mm Hg ( 20 °C)

Toxicity:

LD50 orally in Rabbit: 1144 mg/kg LD50 dermal Rabbit > 400 - < 640 mg/kg

See More 1-Methylimidazole Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Dermal

Skin corrosion, Sub-category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H312 Harmful in contact with skin H314 Causes severe skin burns and eye damage
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P317 Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1-Methylimidazole Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

6 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	Top Selling 1-Methylimidazole CAS: 616-47-7 with Good Price	50 L	Oct 23, 2023
India	1-methyl imidazole	25 KG	Jan 6, 2025
Romania	1-methyl-1H-imidazole	5000 KG	Jan 16, 2026
India	1-Methylimidazole	3 KG	Dec 23, 2025
India	Cuprous Oxide (Copper(I) Oxide)	25 KG	Jan 6, 2025
India	2,2’-BIPYRIDYL AR (22’-DIPYRIDYL)	10 KG	Jan 6, 2025

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