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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > LOXO-101 for Sale > Jinlan 98+ EP/BP/USP Larotrectinib sulfate
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Jinlan 98+ EP/BP/USP Larotrectinib sulfate

Unit Price: Get Latest Price
CAS No.:

1223405-08-0

Grade:

medical grade

Content:

98%

Port:

Shanghai/Ningbo/Qingdao

Brand:

Jinlan

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-03-01

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptides,API,Intermediate

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Larotrectinib sulfate (1223405-08-0)


    Basic Product Description


    CAS Number: 1223405-08-0

    Free Base CAS: 1174044-61-0

    Chemical Name: (R)-2-((5-((3,5-Difluorophenyl)amino)-1H-pyrazol-3-yl)amino)-3-methylbutanamide sulfate (1:1)

    Molecular Formula: C₁₇H₁₉F₂N₅O·H₂SO₄

    Molecular Weight: 445.44 g/mol

    Synonyms: Vitrakvi®, LOXO-101 sulfate

    Related Categories: First-in-class Pan-NTRK Inhibitor, Oral Selective NTRK1/2/3 Tyrosine Kinase Inhibitor (TKI), TRK Fusion Inhibitor, NTRK Fusion-Positive Solid Tumor Therapeutic

    Key Highlight: The first-in-class oral selective pan-NTRK inhibitor targeting NTRK1, NTRK2 and NTRK3 fusion mutations; indicated for adult and pediatric patients with unresectable or metastatic NTRK fusion-positive solid tumors across multiple cancer types; features high selectivity for TRK kinases with potent anti-tumor activity, favorable safety profile, and effective penetration of the central nervous system (CNS) for the treatment of brain metastases.


    Basic Info
    Product Name:

    LOXO-101

    Other Name:

    Larotrectinib sulfate;LOXO-101 sulfate;ARRY-470 sulfate;UNII-RDF76R62ID;RDF76R62ID;(3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide sulfate;(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide sulfate;Vitrakvi (TN);1-Pyrrolidinecarboxamide, N-(5-((2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl)pyrazolo(1,5-a)pyrimidin-3-yl)-3-hydroxy-, (3S)-, sulfate (1:1);1-Pyrrolidinecarboxamide, N-[5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-, (3S)-, sulfate (1:1)

    CAS No.:

    1223405-08-0

    Molecular Formula:

    C21H24F2N6O6S

    InChIKeys:

    PXHANKVTFWSDSG-QLOBERJESA-N

    Molecular Weight:

    526.514

    Exact Mass:

    526.144592

    UNII:

    RDF76R62ID

    NCI Thesaurus Code:

    C156895

    ATC Code:

    L01XE53

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    168.98000

    XLogP3:

    3.45140

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides,API,Intermediate

    Location:

    Room 606, Building 1, Fu Yi Commercial Center, Shangcheng District, Hangzhou City, Zhejiang Province - 1

    Payment Terms:

    100% TT in advance

    Average lead Time:

    275

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Hangzhou Jinlan Pharm-Drugs Technology Co., Ltd (with its export company Hangzhou Royall Import & Export Co.,Ltd.) is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int' l Airport and Shanghai Pudong Int' l Airport, the transportation and production environment are excellent. JINLAN PHARMA mainly business includes: 1) API, Pharmaceutical Intermediates, CMO, CRO, CDMO and so on. 2) Pharmaceutical Equipment such as: Distilled Water Machinery, Mixer, Sterilizer and so on.

    JINLAN PHARM focus on:

    ■ Contrast Agent

    ■ Anti-COVID APIs

    ■ Respiratory System APIs

    ■ Anti-tumor & Anti-Cancer APIs

    ■ Anti-Diabetes APIs

    ■ Anti-HCV & Anti-HBV APIs

    ■ Anti-HIV APIs

    ■ Peptides

    ■ Pharmaceutical Intermediates

    ■ CMO, CRO, CDMO

  • Country Product Purchase Quantity Date Posted
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