Name | Acetyl hexapeptide 38 |
CAS number | 1400634-44-7 |
Description | Acetyl Hexapeptide-38 is a synthetic cosmetic peptide composed of six amino acids with an acetylated N-terminus. The specific sequence, typically a proprietary composition for each commercial ingredient, is designed to target key processes in the skin linked to the appearance of aging. |
Structural formula | |
Molecular Formula |
|
Molecular Weight | g/mol |
Appearance | White powder |
Quality Standard | 99% |
Storage Condition | Cool dry place( away from the light) |
Shelf Life | >2 years if stored properly |
Sample package | Aluminium foil bag |
Commercial package | Aluminium Tin, Fiber drum |
Origin | China |
Acetyl Hexapeptide-38 More Info
Acetyl Hexapeptide-38 is a synthetic cosmetic peptide composed of six amino acids with an acetylated N-terminus. The specific sequence, typically a proprietary composition for each commercial ingredient, is designed to target key processes in the skin linked to the appearance of aging. The acetylation enhances the peptide's stability and skin penetration by increasing its lipophilicity. This compound represents a class of biomimetic peptides engineered for topical application in skincare formulations.
The proposed mechanism of action for this ingredient is multi-faceted and often tailored to its specific sequence. Commonly cited mechanisms for peptides in this category include the inhibition of neurotransmitter release at the neuromuscular junction to reduce the appearance of expression lines, or the stimulation of collagen and other extracellular matrix components like fibronectin and glycosaminoglycans through signaling pathways. By modulating these biological processes, it aims to improve visible skin firmness, elasticity, and smoothness, and to reduce the depth of wrinkles.
The primary application of Acetyl Hexapeptide-38 is exclusively in the cosmetic and personal care industry. It is a premium active ingredient incorporated into anti-aging serums, creams, lotions, and eye treatments. Its function is to deliver targeted cosmetic benefits, improving the aesthetic appearance of the skin rather than treating medical conditions. It is often marketed alongside other peptides, antioxidants, and moisturizing agents in comprehensive anti-aging skincare regimens.
From a formulation chemistry perspective, this peptide is a challenging ingredient due to its sensitivity to degradation by proteases and its need to penetrate the stratum corneum to reach its target. It is typically supplied as a white lyophilized powder or a pre-diluted aqueous solution. Formulators must incorporate it into stable, often serum-based systems with supportive penetration enhancers, ensuring the pH and compatibility with other ingredients preserve its activity. It is used at low concentrations, typically ranging from 1 to 10 parts per million in the final product.
The safety profile of such cosmetic peptides is generally excellent. Due to their biomimetic nature and very low usage concentrations, they are considered non-irritating, non-sensitizing, and safe for topical use. They are not systemically absorbed to a significant degree. Extensive safety assessments, including repeat insult patch testing and ocular irritation studies, are conducted by suppliers to ensure consumer safety. As a cosmetic ingredient, it is not subject to the same rigorous efficacy trials as pharmaceuticals, but its market presence is supported by in vitro data, ex vivo studies, and consumer perception tests demonstrating its cosmetic benefits.
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We can send you a samll free sample, and you only need to pay for the shipping cost.
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For ready stock samples, they are usually shipped within 3 working days after payment received.
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For commercial orders
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