Bremelanotide Dideu

  Product Detail  

Product Name: Validamine
CAS No.: 32780-32-8
Molecular Formula: C₇H₁₃NO₄
Molecular Weight: 175.18 g/mol
Purity: ≥98% (HPLC), customizable
Appearance: White to off-white crystalline powder

Product Overview

Validamine is a specialized aminocyclitol compound featuring a unique cyclohexane-derived structure with multiple hydroxyl groups and a primary amine functionality. This biologically active molecule serves as a critical structural component of acarbose, a clinically proven α-glucosidase inhibitor used in type 2 diabetes management. Validamine's distinctive molecular architecture combines excellent water solubility with potent enzyme inhibitory properties, making it highly valuable for pharmaceutical research, enzyme studies, and development of novel glycosidase-targeting therapeutics. Its well-defined stereochemistry and functional group versatility enable diverse synthetic modifications for creating advanced drug candidates with optimized pharmacological profiles.

Main Applications

Pharmaceutical Research & Drug Development
Essential building block for synthesizing acarbose analogs and novel α-glucosidase inhibitors targeting diabetes, obesity, and metabolic syndrome. Validamine serves as a key intermediate in developing next-generation antidiabetic agents with improved potency, selectivity, and reduced side effect profiles compared to existing therapies.

Enzyme Inhibition Studies
Critical research tool for investigating glycosidase enzyme mechanisms, substrate specificity, and inhibition kinetics. Widely used in biochemical laboratories for studying carbohydrate-processing enzymes involved in glycogen metabolism, glycoprotein processing, and lysosomal storage disorders.

Natural Product Synthesis
Valuable chiral synthon for total synthesis of complex natural products containing aminocyclitol moieties. Researchers utilize validamine as a starting material for developing novel antibiotics, antiviral agents, and bioactive compounds with carbohydrate-mimicking properties.

Glycosidase-Based Diagnostic Reagents
Key component in developing enzyme-based diagnostic kits for detecting glycosidase activity in clinical samples. Applications include screening for genetic disorders, monitoring disease progression, and evaluating therapeutic efficacy in metabolic disease management.

Glycobiology Research
Important tool compound for studying carbohydrate-protein interactions, glycosylation pathways, and cellular recognition processes. Used in developing glycomimetic compounds that modulate immune responses, cell adhesion, and pathogen-host interactions.

Custom Synthesis & CRO Services
High-demand intermediate for contract research organizations engaged in medicinal chemistry programs targeting carbohydrate-processing enzymes. Essential for structure-activity relationship (SAR) studies and lead optimization in antidiabetic drug discovery pipelines.

Product Features

Packaging & Storage

Packaging Options: 100 mg, 500 mg, 1 g, 5 g, 10 g in amber glass vials with PTFE-lined caps under inert atmosphere; custom quantities available
Storage Conditions: Store at -20°C or below in airtight containers, protected from light and moisture to maintain stability
Shelf Life: 24 months when stored under recommended conditions
Transport: Shipped on dry ice with temperature monitoring to ensure product integrity during transit

Why Choose Us

Note: This product is intended for research and pharmaceutical development use only. All specifications subject to change without notice. Contact us for customized purity requirements, special packaging requests, or bulk pricing inquiries. Certificate of Analysis and Safety Data Sheet available upon request.