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API Liquiritigenin

Name: API Liquiritigenin
Brand: Hyper Chem
SKU: pr2604082534
Price: 600 USD
Availability: InStock

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CAS No.:

578-86-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2026-05-08

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Liquiritigenin
CAS number	578-86-9
Description	Liquiritigenin is a flavonoid present in Glycyrrhizae radix.
Related CAS #	69097-97-8 (racemic mixture) 578-86-9
Synonym	Liquiritigenin; (2S)-liquiritigenin; 7,4'-Dihydroxyflavanone; (-)-liquiritigenin; Menerba; MF101; MF 101; MF-101;
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Liquiritigenin More Info

Liquiritigenin (CAS No.: 578-86-9) is a naturally occurring flavanone predominantly extracted from licorice (Glycyrrhiza uralensis). It is recognized for its selective estrogen receptor β (ERβ) agonistic activity and a range of biological properties.

Product Overview:

Chemical Nature: Flavanone (4',7-dihydroxyflavone) with a molecular formula of C15H12O4 and a molecular weight of 256.25 g/mol.

Physical Form: Typically supplied as a yellow crystalline powder, with common packaging sizes ranging from 1 mg to 500 mg. Some suppliers also provide a 1 mL solution at 10 mM in DMSO.

Purity: High-purity grades are available, often exceeding 95% (HPLC), with some specifications reaching up to 99.35%.

Solubility: Soluble in DMSO (up to 100 mg/mL), ethanol, and other organic solvents. It is recommended to sonicate the solution for optimal dissolution.

Storage Conditions: Store the powder at -20°C, protected from light. The solution form is generally stored at -80°C for long-term stability.

Safety: Classified as a research chemical. It should be handled with standard laboratory protective equipment, including gloves and eye protection. Not for human consumption or clinical use.

Biological Activity & Applications:

Selective ERβ Agonist: Liquiritigenin is a highly selective agonist for estrogen receptor β (ERβ), with an EC50 of 36.5 nM for activation of the estrogen response element (ERE) reporter.

Research Applications: Widely used in endocrinology and pharmacology studies, particularly for investigating estrogen receptor signaling pathways, hormone-dependent cancers, and neuroprotective mechanisms.

Therapeutic Potential: Demonstrated anti-tumor, antioxidant, anti-inflammatory, and cholagogue (bile secretion-promoting) effects in various preclinical studies.

Additional Uses: Utilized in cell culture assays to modulate cell proliferation and protect against oxidative stress.

Product Availability:

Suppliers: Liquiritigenin is stocked by multiple reputable chemical vendors, including MedChemExpress, APExBIO, and local Chinese distributors. Prices and stock availability may vary, with most vendors offering rapid shipment and free solubilization services.

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Basic Info

Product Name:

Liquiritigenin

Other Name:

4H-1-Benzopyran-4-one,2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-,(2S)-;Flavanone,4′,7-dihydroxy-;4H-1-Benzopyran-4-one,2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-,(S)-;(2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;Liquiritigenin;7,4′-Dihydroxyflavanone;4′,7-Dihydroxyflavanone;(-)-(2S)-7,4′-Dihydroxyflavanone;(2S)-Liquiritigenin;(-)-(S)-4′,7-Dihydroxyflavanone;(-)-Liquiritigenin;Menerba;(2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one;2885-30-5;16006-91-0;17002-53-8

CAS No.:

578-86-9

Molecular Formula:

C15H12O4

InChIKeys:

InChIKey=FURUXTVZLHCCNA-AWEZNQCLSA-N

Molecular Weight:

256.25

Exact Mass:

256.25

UNII:

T194LKP9W6

DSSTox ID:

DTXSID90206493

HScode:

29329990

Categories:

Chinese Herbs

Characteristics

PSA:

66.8

XLogP3:

2.2

Appearance:

Solid

Density:

1.4±0.1 g/cm3

Melting Point:

182-183 °C

Boiling Point:

529.5°C at 760 mmHg

Flash Point:

207℃

Refractive Index:

1.662

See More Liquiritigenin Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Liquiritigenin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	liquiritigenin	2 G	Apr 8, 2026

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