PE 22-28 (Epithalamin Active Fragment / Epitalon Short Peptide)
Basic Chemical Specifications
- Amino Acid Sequence: Ala-Glu-Asp-Gly-Pro-Leu-Gly
- Molecular Formula: C₂₉H₄₉N₉O₁₃
- Molecular Weight: 727.75 Da
- Appearance: White lyophilized crystalline powder
- Standard Pack: 10mg / 20mg / 50mg per sterile glass vial
- HPLC Purity: ≥99% research grade
- Disclaimer: For laboratory research use only, not for human injection, oral intake or clinical treatment
Product Introduction & Core Mechanism
PE 22-28 is the core bioactive heptapeptide fragment isolated from Epithalamin, a natural pineal gland polypeptide complex. It acts as a potent epigenetic geroprotector targeting telomere maintenance and pineal endocrine balance, with stronger targeted activity than crude pineal extracts.
Core research mechanisms:
- Activate telomerase & protect telomere length
Upregulate endogenous telomerase activity in somatic cells, slow telomere shortening, delay cellular replicative senescence and extend cell lifespan in lab models. - Regulate pineal-melatonin endocrine axis
Stimulate normal melatonin secretion from pinealocytes, correct circadian rhythm disorders, improve sleep cycle balance and stabilize biorhythm. - Comprehensive anti-oxidation & anti-inflammation
Reduce excess reactive oxygen species and pro-inflammatory cytokines, relieve chronic oxidative stress linked to aging and metabolic decline. - Immune system rejuvenation
Improve age-related immune suppression, balance T-lymphocyte activity and reduce immunosenescence markers. - Neuroprotective function
Protect brain nerve cells from oxidative damage, support cognitive maintenance and slow age-dependent neural function degradation.
Our PE 22-28 Product Competitive Advantages
- Ultra-high purity ≥99%
Every batch passes HPLC and LC-MS mass spectrum identification. Complete COA, HPLC chromatogram, heavy metal and endotoxin test reports are provided for all bulk orders; no degraded peptide fragments or impurity residues. - Vacuum freeze-drying technology
Full moisture removed without preservatives, fully locks complete peptide biological activity. Lyophilized solid form avoids hydrolysis and oxidation during long-distance air & sea cross-border shipping, stable activity for a 24-month shelf life. - GMP clean-room sterile production
Independent single sealed vial packaging to avoid cross-contamination. Custom private labels, bottle sizes and bulk packing service available for global resellers and lab suppliers. - Excellent water solubility
Rapidly dissolves in bacteriostatic water to form clear transparent solution without sediment, easy for precise lab dosage preparation. - Complete professional technical support
We supply detailed reconstitution guide, storage specification, laboratory dosage reference and full batch traceability documents.
Storage & Reconstitution Instructions
- Unopened lyophilized powder: Long-term storage at -20°C away from light and humidity, shelf life up to 24 months; short-term transit storage at 2–8°C is acceptable.
- Reconstitution solvent: Sterile bacteriostatic water
- Operation tip: Slowly inject solvent along the inner vial wall, swirl gently instead of violent shaking to prevent peptide aggregation and activity loss.
- Reconstituted solution: Seal tightly and refrigerate at 2–8°C, finish use within 14 days; avoid repeated freeze-thaw cycles.
Global Wholesale Cooperation Support
- Flexible MOQ & tiered large-volume discount for stable VIP long-term partners
- Low-risk dedicated shipping channels for USA, EU, Brazil, Australia with lower customs detention probability
- Exclusive one-on-one VIP account manager, fast response and professional reshipping solution for logistics issues
Version 2 Short WhatsApp / Social Media Selling Copy
PE 22-28 Lyophilized Peptide | 99% High Purity Geroprotective Heptapeptide
Core active fragment of pineal gland polypeptide Epithalamin.
Key research directions: activate telomerase, protect telomere, regulate melatonin secretion, improve circadian rhythm, anti-oxidation and delay cellular senescence.
✅ Purity ≥99% verified by HPLC & mass spectrum
✅ Specifications: 10mg / 20mg / 50mg per sterile vial
✅ Full set of official COA testing documents attached
✅ Freeze-dried stable form suitable for worldwide delivery
✅ Clear solution after reconstitution, convenient lab operation
✅ Custom packaging & favorable bulk wholesale price
Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.
Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
Our Commitment: Integrity, efficiency, and transparency in every transaction.
Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.
We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together.
We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.
We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.
We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.