High Purity 5-Amino-1MQ CAS 42464-96-0 NNMT Inhibitor 5mg 50mg per Vial 10 Vials per Kit for Metabolic Research

High Purity 5-Amino-1MQ CAS 42464-96-0 NNMT Inhibitor 5mg 50mg per Vial 10 Vials per Kit for Metabolic Research

5-Amino-1MQ (5-Amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), a key enzyme involved in cellular metabolism and energy regulation. NNMT functions by methylating nicotinamide, which reduces the availability of this precursor for NAD+ biosynthesis. By inhibiting NNMT activity, 5-Amino-1MQ helps preserve nicotinamide levels and supports NAD+ production in cells.

This product has been studied in preclinical research for its effects on cellular energy metabolism, adipocyte function, and muscle cell differentiation. It is supplied as a sterile powder in sealed vials, ensuring high stability and bioactivity for research purposes only.

The compound exhibits high cell membrane permeability, allowing effective cellular uptake. Research applications include metabolic studies, cellular differentiation investigations, and NAD+ pathway research. Each vial is hermetically sealed to prevent moisture absorption and contamination. The product is intended for in vitro and in vivo research applications, including cell culture studies, animal model experiments, metabolic assays, and biochemical analyses.

Note: For laboratory research use only. Not for human consumption, medical treatment, therapeutic injection, or veterinary application.

Product Advantages / Preliminary Research Applications

Product Advantages:

• High purity (≥99% by HPLC) for reliable and reproducible research outcomes

• Selective NNMT inhibitor with IC50 of 1.2 μM

• High cell membrane permeability for effective intracellular activity

• Sterile powder form ensures long-term stability and easy handling

• Sealed vials prevent contamination and moisture absorption

• Available in multiple dosages (5mg, 50mg per vial) to suit different experimental needs

Preliminary Research Applications:

• NNMT Enzyme Studies: Investigating nicotinamide methylation and its effects on NAD+ biosynthesis

• Metabolic Research: Examining cellular energy regulation and metabolic pathway modulation

• Adipocyte Research: Studying fat cell metabolism and lipid accumulation mechanisms

• Muscle Cell Differentiation: Investigating myoblast differentiation and muscle stem cell function

• NAD+ Research: Exploring NAD+ salvage pathway regulation and cellular energy homeostasis

• Receptor Binding Assays: Characterizing NNMT inhibitor binding and selectivity profiles

• Cellular Aging Studies: Examining NAD+-related pathways in cellular health and aging research

Packaging Structure (From Outer to Inner)

Level Description

Outer Packaging Standard cardboard box

Middle Packaging Product box (branded/plain) containing a plastic box inside

Inner Packaging Plastic box holding 10 glass vials with foam or partition protection

Vial Clear glass vial, aluminum-plastic flip-off seal, labeled with product name, dosage, and batch number

Each Plastic Box Contains:
10 vials of 5-Amino-1MQ (5mg/50mg per vial).

The vial is individually sealed with label.

Foam or plastic partition to prevent vials from bumping into each other

Shipping Methods & Delivery Time
Shipping Method Cost Delivery TimeSpecial Line/ Express $40 (under 5kg) ~14 days
UK Special Line Same as above ~25 days (slightly delayed)
UPS / FedEx $70 7-10 daysShipping Policies

Policy Details
Free Shipping On orders over $1000
Remote Area Fee Some remote areas may incur an extra $35 (as determined by FedEx/UPS)
Lead Time 3-5 business days after payment confirmation

Frequently Asked Questions (FAQ)
Q1: Can I get a sample before placing an order?

Yes, samples are available upon request. Samples are not provided for free. You will need to pay for both the sample cost and the shipping fee. The sample fee will be deducted from your bulk order payment once you proceed with a formal order.

Q2: What payment methods do you accept?

We accept wire transfer (T/T), PayPal, and bank transfer. You may choose the most convenient method for you.

Q3: How and when can I receive my order after payment?

Small quantity orders: Shipped via international express (DHL, FedEx, UPS, etc.). Delivery time: 7-10 days after shipment.

Large quantity orders: Shipped by sea. Delivery time: 15-30 days depending on the destination port.

Special line: ~14 days delivery time (under 5kg, $40).

Q4: Can I use my own label or packaging?

Yes, OEM service is available for bulk orders. We can customize labels, vial dosage, vial cap color, and packaging according to your requirements. Please contact us for details.

Q5: What is your MOQ (Minimum Order Quantity)?

Retail MOQ: 1 kit/dosage/item

Customized packaging (e.g., custom vial size, cap color): 20-50 kits/dosage/item

Q6: Do you provide a Certificate of Analysis (COA) with each order?

Yes, each batch comes with a COA (HPLC purity test report). Third-party testing is also available upon request.

Q7: How should I store the peptide?

Store at -20°C, protected from light, and keep sealed. Once reconstituted, refrigerate at 2-8°C and use within the recommended timeframe.

Q8: What documents will be included with my shipment?

Commercial invoice, packing list, COA, and MSDS will be included with each shipment.