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Home > Food Additives > Sweeteners > Neotame for Sale > Neotame High Purity Functional Sweetener Additives with Best Price
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Neotame High Purity Functional Sweetener Additives with Best Price

TDS 6 Inquiries

Unit Price:

$18-20/KG FOB

Get Latest Price
CAS No.:

165450-17-9

Grade:

Food Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-06-27

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

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    Neotame is a high-intensity, low-calorie artificial sweetener belonging to the aspartame family. Chemically known as N-(3,3-dimethylbutyl)-L-α-aspartyl-L-phenylalanine 1-methyl ester, it was developed as a next-generation sweetener with improved stability and broader application potential. Approved by major food safety authorities including the FDA and EFSA, neotame is widely used in the food and beverage industry.



    Neotame is a white to off-white crystalline powder with a clean, sugar-like sweetness profile. It is approximately several thousand times sweeter than sucrose, making it one of the most potent sweeteners available. Its molecular formula is C₂₀H₃₀N₂O₅, with a molecular weight around 378.5 g/mol. Neotame is freely soluble in water and exhibits excellent stability across a wide range of pH levels (2–8) and high temperatures. Unlike aspartame, neotame does not break down into phenylalanine, making it safe for individuals with phenylketonuria. Its solubility and heat stability allow it to be used in baking, pasteurization, and other thermal processes.



    The global market for neotame is growing steadily, driven by rising consumer demand for reduced-sugar and zero-calorie products. Increasing health awareness, obesity concerns, and diabetes prevalence fuel the shift toward non-nutritive sweeteners. Neotame offers advantages over older sweeteners like aspartame and saccharin, including superior stability and no bitter aftertaste. Food manufacturers are actively incorporating it into reformulated products. The market is expected to expand further as clean-label trends evolve and new applications in pharmaceuticals and nutraceuticals emerge.



    Neotame’s versatility allows it to be used in a wide range of products. In beverages, it sweetens soft drinks, fruit juices, flavored waters, and powdered drink mixes without compromising taste during storage. In dairy products, it is used in yogurts, ice cream, and flavored milk, where heat processing is required. Bakery goods benefit from neotame’s thermal stability; it withstands oven temperatures without losing sweetness. It is also found in confectionery, chewing gum, tabletop sweeteners, sauces, dressings, and even pharmaceuticals such as syrups and chewable tablets. Additionally, neotame works synergistically with other sweeteners or bulkers to reduce costs and improve taste profiles.



    Several other non-caloric and low-calorie sweeteners are widely used alongside neotame. **Stevia** (steviol glycosides) is a plant-derived sweetener with a growing clean-label appeal. **Erythritol**, a sugar alcohol, provides bulk and a cooling effect, often blended with high-potency sweeteners. **Sucralose** is a chlorinated sucrose derivative valued for its exceptional heat stability and sugar-like taste. **Aspartame** remains common in carbonated beverages and tabletop packets, though it has stability limitations. **Monk fruit extract** is another natural option, prized for its intense sweetness and antioxidant properties. **Saccharin** and **cyclamate** are older sweeteners still used in some markets, often in combination blends. Each sweetener has unique benefits, and manufacturers often combine multiple types to achieve optimal flavor and cost-efficiency.


    In summary, neotame stands out for its potent sweetness, stability, and safety, positioning it as a key player in the evolving sweetener landscape alongside both natural and synthetic alternatives.

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    Test Item Specification
    Appearance White crystalline granular or powder
    mesh 20-60mesh/20-30mesh/30-60mesh/as you need
    Taste Practically odorless with a very sweet taste
    Melting range 119-123ºC
    Assay 99.5-100.5 %(on dry basis)
    Solubility Very soluble in water, slightly soluble in eth-anol
    pH value 5-7
    Loss on drying ≤0.2%
    Ash ≤0.1%
    Lead(Pb) ≤0.5 mg/kg
    As ≤0.3 mg/kg
    Reducing Sugars ≤0.3%
    Ribitol and glycerol ≤0.1%
    Cont of bacteria ≤300 cfu/g
    Yeast and Moulds ≤100 cfu/g
    Coliform ≤0.3 MPN/g
    Pathogens Negative


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    Due to its sugar-like bulk and browning capability, D-Allulose is highly versatile in food production. In baked goods, it provides the necessary structure, moisture retention, and caramelization that other zero-calorie sweeteners cannot achieve. In beverages, it dissolves readily to provide a clean, sugar-like taste without the bitter aftertaste associated with stevia or artificial options. It is also utilized in confectionery, dairy products (such as yogurt and ice cream), and pharmaceuticals, where its low glycemic index offers functional benefits for blood sugar management. Beyond sweetness, studies suggest D-Allulose possesses anti-inflammatory, antihyperlipidemic, and neuroprotective effects, positioning it as a functional ingredient for metabolic health.


    Other Popular Sweeteners


    While D-Allulose is gaining traction, the broader sweetener market remains dominated by several other categories:

    • Stevia: A natural, high-intensity sweetener extracted from the Stevia plant. It is calorie-free and significantly sweeter than sugar but can impart a distinct licorice-like aftertaste, often mitigated through blending with other molecules like Reb M.


    • Erythritol: A sugar alcohol (polyol) that provides about 70% of the sweetness of sugar with nearly zero calories. It is commonly used in "keto" and low-carb products, though high doses can cause digestive discomfort.


    • Monk Fruit Extract: Another natural, zero-calorie sweetener. It contains antioxidants called mogrosides and has a clean taste profile, though it is often significantly more expensive than other alternatives.


    • Sucralose: An artificial sweetener derived from sucrose. It is heat-stable and intensely sweet but has faced consumer scrutiny regarding synthetic origins despite regulatory approval.

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    Certificates

    Basic Info
    Product Name:

    Neotame

    Other Name:

    L-Phenylalanine,N-(3,3-dimethylbutyl)-L-α-aspartyl-,2-methyl ester;L-Phenylalanine,N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-,1-methyl ester;Neotame;Mirasee;E 961;Mirasee 200;L,L-Neotame

    CAS No.:

    165450-17-9

    Molecular Formula:

    C20H30N2O5

    InChIKeys:

    InChIKey=HLIAVLHNDJUHFG-HOTGVXAUSA-N

    Molecular Weight:

    378.46

    Exact Mass:

    378.46

    EC Number:

    253-404-6

    UNII:

    VJ597D52EX

    DSSTox ID:

    DTXSID50167950

    HScode:

    2924299090

    Categories:

    Sweeteners

    Characteristics
    PSA:

    105

    XLogP3:

    -0.1

    Appearance:

    white to off-white powder

    Density:

    1.1±0.1 g/cm3

    Melting Point:

    83-85°C

    Boiling Point:

    565.3°C at 760 mmHg

    Flash Point:

    277.9±32.9 °C

    Refractive Index:

    1.530

    Water Solubility:

    In water, 14.4 mg/L at 25 deg C (est)

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    2.71X10-11 mm Hg at 25 deg C (est)

    Specific rotation:

    D -54.84° (c = 1 in methanol); D20 -39.8° (c = 0.5 in water)

    Taste:

    Clean sweet taste without bitter, metallic or off flavors

    PH:

    5,0-7,0 (0,5 % aqueous solution)

    Henrys Law Constant:

    Henry's Law constant = 2.29X10-17 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 4.11; pKa2 = 7.70; pKa3 = 6.45

    Experimental Properties:

    White crystalline powder from ethyl acetate/hexane; mp 80-83 deg ; also reported as mp 80.9-83.4 °C from aqueous methanol. SPecific optical rotation: -58.84 deg at 25 °C/D (c = 1 in methanol); -39.8 deg at 20 °C/D (c = 0.5 in water). pKa1 = 3.01; pKa2 = 8.02. pI: 5.5. Calorie value: <1.2 kH/g. Solubility in water (g/L): 10.6 (15 °C), 12.6 (25 °C), 47.5 (60 °C); in ethyl acetate (g/L): 43.6 (15 °C), 77 (25 °C), >1000 (60 °C); in absolute ethanol (g/L): approximately 950 (25 °C) /Neotame monohydrate/|Hydroxyl radical reaction rate constant = 1.10X10-10 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

    Location:

    Changqing 5th Road, Jianghan District

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    5

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2020

    Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

  • Inquiry History
    6 Inquiries
    Country Product Purchase Quantity Date Posted
    Poland

    neotame

    100 KG Apr 14, 2026
    Nigeria

    NEOTAME

    1 20' Fcl Oct 15, 2024
    Pakistan

    Neotame

    250 KG Feb 2, 2024
    Pakistan

    Neotame

    1000 KG Jan 31, 2024
    Pakistan

    Neotame powder 8000times

    10 KG Dec 14, 2023
    Poland

    WS-3; WS-23; NEOTAME; SUCRALOSE

    1 MT Jan 9, 2025
    Post an enquiry for this product
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