High Quality Raw Powder in stock with Fast Safe Delivery TSM10/99%

  Product Detail  

Product Packing: 10 vials in a box (Customized size，label, box according to customer's requirements)

Shipping Condition:Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years), after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 2–4 weeks. 

Name:Rain

Whatsapp:+852 69948372

Email:rain@anymang.cn

Triple Agonist Design :

GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote secretion.

GIP receptor: Retatrutide enhances sensitivity and regulate central satiety signals.

Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.

The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

Mechanism of Action and Molecular Structure of Retatrutide:

1)Triple Agonist Design
- GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote secretion.
- GIP receptor: Retatrutide enhances insulin sensitivity and regulate central satiety signals.
- Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.
The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

2) Structural Optimization
- Based on the GIP skeleton modification, non-natural amino acids (such as α-methylleucine at position 13) are introduced to enhance receptor affinity.
- The half-life is extended to 7 days through fatty acid side chain modification