1. Product Overview
AHK-CU is a high-purity synthetic copper-complexed tripeptide with premium pharmaceutical and cosmetic grade specifications. As an optimized structural analog of the classic GHK-Cu peptide, it features an upgraded Alanine-Histidine-Lysine sequence stably bound to copper ions. Produced via standardized solid-phase synthesis with ≥99% HPLC purity, this bioactive peptide presents stable molecular conformation, ultra-low impurity content and excellent batch consistency. With superior cell permeability and dual regenerative & anti-inflammatory properties, AHK-CU specifically targets hair follicle vitality and dermal tissue repair. It is widely applied in hair regrowth research, scalp microenvironment optimization, skin anti-aging repair and high-end peptide formulation development.
2. Basic Specifications
- Product Name: AHK-CU Pharmaceutical Grade Peptide
- Sequence: Alanine-Histidine-Lysine Copper Complex (AHK-Cu)
- Molecular Weight: 451.39 Da
- CAS Number: 682809-81-0
- Purity: ≥99.0% (HPLC)
- Appearance: Fine light blue sterile lyophilized powder
- Solubility: Fully soluble in sterile water and aqueous solvent
- Core Feature: Follicle regeneration & dermal repair copper tripeptide
- Grade Standard: Pharmaceutical raw material grade, low endotoxin, heavy metal compliant
- Storage: -20°C sealed, dry and protected from light
- Shelf Life: 24 months under standard storage conditions
3. Mechanism of Action
AHK-CU exerts targeted regenerative regulation through activating multiple core biological signaling pathways. It specifically binds to copper transport receptors on dermal papilla cells, upregulates the Wnt/β-catenin pathway to promote hair follicle stem cell proliferation and differentiation, effectively prolonging the follicle growth phase. Meanwhile, it elevates VEGF expression to enhance scalp microcirculation and increases SOD antioxidant activity to eliminate follicular oxidative stress.
Different from ordinary hair care ingredients that only improve surface scalp condition, AHK-CU fundamentally reverses follicle miniaturization by inhibiting TGF-β1-mediated follicle fibrosis and cellular apoptosis. It balances inflammatory and regenerative gene expression, repairs aging dermal matrix, and achieves long-term stable follicle vitality and skin tissue renewal without hormonal interference.
4. Core Benefits & Applications
- Hair Follicle Activation & Regrowth: Awakens dormant hair follicles, extends the anagen growth phase, inhibits follicle atrophy, and effectively improves thinning hair and sparse hair issues.
- Scalp Microenvironment Optimization: Boosts scalp blood microcirculation, removes oxidative free radicals, relieves scalp inflammation, and reduces stress and DHT-induced hair loss.
- Dermal Anti-Aging & Repair: Stimulates endogenous collagen and elastin synthesis, repairs damaged skin extracellular matrix, improves skin elasticity and relieves fine lines.
- Anti-Inflammatory & Antioxidant Protection: Downregulates pro-inflammatory factors, reduces chronic low-grade scalp and skin inflammation, and enhances tissue antioxidant defense capacity.
- Professional Research Use: High-purity API for follicle regeneration pharmacology, scalp health research, skin tissue repair mechanism and high-end cosmetic peptide formulation development.
5. Advantages of 99% Pharmaceutical-Grade AHK-CU
- Upgraded optimized structure: Improved molecular stability compared with traditional GHK-Cu, stronger follicle targeting and longer lasting efficacy
- Hormone-free regeneration mechanism: No DHT suppression or endocrine interference, safe for long-term scalp and skin conditioning
- Dual hair and skin efficacy: Integrates hair regrowth, anti-inflammation and dermal anti-aging repair in one peptide
- ≥99% HPLC ultra-high purity, strict single impurity control, zero batch difference for synthetic copper tripeptide
- Low endotoxin and ultra-low heavy metals, fully compliant with pharmaceutical and high-end cosmetic raw material standards, excellent solubility and formulation stability
6. Safety & Usage Features
AHK-CU is a high-safety bionic copper peptide with excellent biological and skin tolerance. It features mild physiological regulation, no cytotoxicity, no irritation, no hormone dependence and no cumulative side effects. Standard cyclic use safely activates follicle vitality, optimizes scalp health and repairs aging skin tissue, suitable for long-term scalp and skin sub-health conditioning and high-standard biomedical research applications.
Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.
Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
Our Commitment: Integrity, efficiency, and transparency in every transaction.
As a professional original peptide manufacturer integrating independent R&D, production and sales, we stand out in the global peptide industry with reliable quality, stable supply and cost-effective solutions, serving global clients engaged in scientific research, biotech, healthcare and cosmetic fields.
Quality is our core competitive advantage. We strictly follow standardized production and quality control systems, with all peptide products including Vesugen polypeptide tested by high-precision HPLC to ensure a purity of 98%-99%. Equipped with independent sterile laboratories and advanced testing equipment, we conduct full-process monitoring from raw material screening, synthesis, purification to lyophilization. Every batch of products comes with complete test reports, guaranteeing high stability, high activity and zero impurities, fully meeting international research and commercial application standards.
We own standardized automated production lines to support flexible and scalable production. We efficiently handle orders ranging from small-batch trial samples to large-scale bulk customization, realizing stable mass production while shortening delivery cycles. Different from middlemen and distributors, we have full control over production links, effectively cutting intermediate costs and offering factory-direct competitive prices without compromising product quality.
Supported by a professional technical team with years of peptide synthesis experience, we master mature lyophilization and peptide modification technologies. Besides conventional peptide products, we provide one-stop customized services including exclusive sequence synthesis, formula optimization and professional reconstitution guidance. We offer accurate technical instructions for product dilution, concentration calculation and storage, solving all technical problems for clients.
We adhere to strict warehouse and logistics management. Lyophilized peptides are stored in low-temperature and light-proof environments to ensure long-term activity retention. We provide secure vacuum packaging and global fast delivery, along with thoughtful after-sales support. Choosing us means you gain high-quality products, professional technology, stable supply and cost-effective prices all in one reliable partner.
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