Pilsicainide hydrochloride
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Pilsicainide hydrochloride
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CAS No:
88069-49-2
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Formula:
C17H24N2O.ClH
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Chemical Name:
Pilsicainide hydrochloride
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Synonyms:
1H-Pyrrolizine-7a(5H)-acetamide,N-(2,6-dimethylphenyl)tetrahydro-,hydrochloride (1:1);1H-Pyrrolizine-7a(5H)-acetamide,N-(2,6-dimethylphenyl)tetrahydro-,monohydrochloride;SUN 1165;Pilsicainide hydrochloride;Sunrythm;1H-Pyrrolizine-7a(5H)-acetamide N-(2,6-dimethylphenyl)tetrahydro-,hydrochloride
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CAS No:
Safety Information
3
|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity. (See all compounds classified as Sodium Channel Blockers.)
1H-pyrrolizine-7a(5H)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, hydrochloride (1:1)
Computed Properties
Molecular Weight:308.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:308.1655411
Monoisotopic Mass:308.1655411
Topological Polar Surface Area:32.3
Heavy Atom Count:21
Complexity:348
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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