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Tiadinil

Tiadinil structure

CAS No:
223580-51-6
Formula:
C11H10ClN3OS
Chemical Name:
Tiadinil
Synonyms:
1,2,3-Thiadiazole-5-carboxamide,N-(3-chloro-4-methylphenyl)-4-methyl-;N-(3-Chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide;Tiadinil;V-Get;Saixianjunan;1135441-70-1
Categories:
Analytical Chemistry > Standard

Description

Tiadinil is a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles; insecticide agent.

Tiadinil is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-methyl-1,2,3-thiadiazole-5-carboxylic acid with the amino group of 3-chloro-4-methylaniline. It is a fungicide used particularly for the control of fungal diseases in rice. It has a role as an antifungal agrochemical. It is a monocarboxylic acid amide, a member of monochlorobenzenes, a member of thiadiazoles, an organosulfur compound and an anilide fungicide.

Tiadinil Basic Attributes

Molecular Weight：

267.73

Exact Mass：

267.73

EC Number：

606-997-4

UNII：

T89DDV3BQZ

DSSTox ID：

DTXSID9058024

Characteristics

PSA：

83.1

XLogP3：

Density：

1.4±0.1 g/cm3

Melting Point：

111-113°C

Refractive Index：

1.663

Water Solubility：

9.6 [ug/mL]

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

20-51/53

safety instructions：

Marks：

Xn,N

Precautionary statement(s)：

P261, P271, P304+P312, P304+P340, P312

Hazard Statements：

H332

GHS Classification：

|Warning|H332 (99.22%): Harmful if inhaled [Warning Acute toxicity, inhalation]|P261, P271, P304+P312, P304+P340, and P312|Aggregated GHS information provided by 128 companies from 2 notifications to the ECHA C&L Inventory.|Danger|H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]|P201, P202, P260, P264, P270, P281, P308+P313, P314, P405, and P501

Drug Information

MeSH Entry Terms：

N-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide

Tiadinil Use and Manufacturing

Methods of Manufacturing

After condensing ethyl acetoacetate and carbazate in ethanol, the ring is closed with thionyl chloride to obtain 4-methyl-1, 2, 3-thiadiazole-5-carboxylate. After it is hydrolyzed to the corresponding acid, it is chlorinated with thionyl chloride to obtain the corresponding acid chloride, and then reacted with 3-chloro-4-methylaniline under the action of an acid binding agent to obtain thiazamide.

Uses

The novel systemic fungicide can be quickly transferred to other parts through root absorption. The agent itself has poor inhibitory activity against pathogens, and can prevent the disease mycelium from invading adjacent healthy cells, and can induce the generation of disease resistance genes. It is suitable for water use and has a long lasting period. It has a good control effect on leaf rice blast and ear rice blast, and is especially suitable for rice seedling boxes. The effect of medication is particularly good in the early stages of the disease. To control leaf rice blast and spread on water, the recommended dosage is 1.8kg active ingredient/hm2. It should be used 7 to 20 days before the onset of disease. Mixing with fipronil and imidacloprid can control rice blast, weevils, leafhoppers, planthoppers and other pests.

Use Classification：

Agrochemicals -> Fungicides

Computed Properties

Molecular Weight:267.74
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:267.0233108
Monoisotopic Mass:267.0233108
Topological Polar Surface Area:83.1
Heavy Atom Count:17
Complexity:292
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Thionyl chloride

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1,2,3-Thiadiazole-5-carboxamide,N-(3-chloro-4-methylphenyl)-4-methyl-

CAS No.: 223580-51-6

Content: 99.00%

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TIADINIL KEK

CAS No.: 223580-51-6

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