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PGA1

PGA1 structure

CAS No:
14152-28-4
Formula:
C20H32O4
Chemical Name:
PGA1
Synonyms:
Prosta-10,13-dien-1-oic acid,15-hydroxy-9-oxo-,(13E,15S)-;3-Cyclopentene-1-heptanoic acid,2-(3-hydroxy-1-octenyl)-5-oxo-;(13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid;15-Hydroxy-9-oxoprosta-10,13-dienoic acid;Prostaglandin A1;PGA1;Prostaglandin E1-217;15α-Hydroxy-9-ketoprosta-10,13-dienoic acid;15α-Hydroxy-9-oxo-10,13E-prostadienoic acid;6229-44-3
Categories:
Analytical Chemistry > Standard

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Description

Solid

PGA1 Basic Attributes

Molecular Weight：

336.47

Exact Mass：

336.47

EC Number：

234-237-8

HScode：

2937500000

Characteristics

PSA：

74.6

XLogP3：

3.61

Appearance：

white to yellow crystalline solid

Density：

1.0192 (rough estimate)

Melting Point：

43°C

Boiling Point：

392.93°C (rough estimate)

Flash Point：

276.7±26.6 °C

Refractive Index：

1.4434 (estimate)

Water Solubility：

acetone: 10 mg/mL, clear

Storage Conditions：

−20°C

Vapor Pressure：

1.44E-12mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

RTECS Number：

GY5977900

Precautionary statement(s)：

P201, P202, P264, P270, P281, P301+P310, P308+P313, P321, P330, P405, P501

Hazard Statements：

H301

PGA1 Use and Manufacturing

This eicosanoid (FWfree-acid = 336.47 g/mol; CAS 14152-28-4; Symbol: PGA1) induces apoptosis and stimulates the expression of stress genes. The structure and role of the prostaglandin A1 was investigated by Bergstr'm and Samuelsson, who shared the 1982 Nobel Prize in Physiology or Medicine for their pioneering work on the eicosanoids. Target(s): CYP4F2; DNA topoisomerase II; HIV-1 transcription; 3ahydroxysteroid dehydrogenase, NADP+-dependent; IkB kinase; Mayaro virus replication; stress-induce